In vitro and in vivo anticancer effect of pH-responsive paclitaxel-loaded niosomes

Abstract In this study, paclitaxel (PTX)-loaded pH-responsive niosomes modified with ergosterol were developed. This new formulation was characterized in terms of size, morphology, encapsulation efficiency (EE), and in vitro release at pH 5.2 and 7.4. The in vitro efficacy of free PTX and niosome/PT...

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Auteurs principaux: Mahmood Barani, Mohammad Reza Hajinezhad, Saman Sargazi, Abbas Rahdar, Sheida Shahraki, Azadeh Lohrasbi-Nejad, Francesco Baino
Format: article
Langue:EN
Publié: Springer 2021
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Accès en ligne:https://doaj.org/article/14bfcb953f5743f69b1ff21efd0bf119
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