Small Incision Lenticule Extraction (SMILE) in Patients with Corneal Guttae

Bu Ki Kim,1 Young Taek Chung2 1Onnuri Smile Eye Clinic, Gangnam-Daero 65 Gil, Seoul, Seocho-gu, Republic of Korea; 2Onnuri Eye Hospital, Baekje-Daero, Wansan-Gu, Jeonju-si, Jeollabuk-do, Republic of KoreaCorrespondence: Young Taek Chung 325, Baekje-Daero, Wansan-Gu, Jeonju-si, Jeollabuk-do, Republic...

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Autores principales:	Kim BK, Chung YT
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	small incision lenticule extraction smile corneal guttae fuchs endothelial corneal dystrophy Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/14c32d078e0e49c796f83b05841d635a
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spelling	oai:doaj.org-article:14c32d078e0e49c796f83b05841d635a2021-12-02T10:25:37ZSmall Incision Lenticule Extraction (SMILE) in Patients with Corneal Guttae1177-5483https://doaj.org/article/14c32d078e0e49c796f83b05841d635a2020-08-01T00:00:00Zhttps://www.dovepress.com/small-incision-lenticule-extraction-smile-in-patients-with-corneal-gut-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Bu Ki Kim,1 Young Taek Chung2 1Onnuri Smile Eye Clinic, Gangnam-Daero 65 Gil, Seoul, Seocho-gu, Republic of Korea; 2Onnuri Eye Hospital, Baekje-Daero, Wansan-Gu, Jeonju-si, Jeollabuk-do, Republic of KoreaCorrespondence: Young Taek Chung 325, Baekje-Daero, Wansan-Gu, Jeonju-si, Jeollabuk-do, Republic of KoreaTel +82 63 277 2774Email ytchungc@hanmail.netPurpose: To report 12-month results of small incision lenticule extraction (SMILE) in the treatment of myopia with corneal guttae (CG).Methods: We conducted a retrospective analysis of 12 eyes from six patients who had preoperative CG without clinical sign of Fuchs’ endothelial corneal dystrophy (FECD) and had SMILE for correction of myopia. Preoperative and 12-month postoperative measurements included uncorrected distance visual acuity (UDVA), spherical equivalent (SE), endothelial cell density (ECD), the coefficient of variation (CV), the percentage of hexagonal cells (HEX), and central corneal thickness (CCT). The changes in ECD, CV, HEX, and CCT after SMILE were subjected to statistical analysis.Results: Twelve months postoperatively, the mean SE was − 0.10 ± 0.32 D and all eyes had a UDVA of 0 logMAR or better. No eyes developed corneal edema or other complication during the follow-up period. There were no significant changes in the ECD, CV, or HEX at 12 months (all p> 0.05).Conclusion: SMILE yielded improvement in visual acuity and no adverse effects to corneal endothelial cells were found when correcting myopia or myopic astigmatism in patients with CG. However, studies with a greater number of patients and longer follow-up periods are needed to establish the long-term outcomes and safety.Keywords: small incision lenticule extraction, SMILE, corneal guttae, Fuchs’ endothelial corneal dystrophyKim BKChung YTDove Medical Pressarticlesmall incision lenticule extractionsmilecorneal guttaefuchs endothelial corneal dystrophyOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 2485-2490 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	small incision lenticule extraction smile corneal guttae fuchs endothelial corneal dystrophy Ophthalmology RE1-994
spellingShingle	small incision lenticule extraction smile corneal guttae fuchs endothelial corneal dystrophy Ophthalmology RE1-994 Kim BK Chung YT Small Incision Lenticule Extraction (SMILE) in Patients with Corneal Guttae
description	Bu Ki Kim,1 Young Taek Chung2 1Onnuri Smile Eye Clinic, Gangnam-Daero 65 Gil, Seoul, Seocho-gu, Republic of Korea; 2Onnuri Eye Hospital, Baekje-Daero, Wansan-Gu, Jeonju-si, Jeollabuk-do, Republic of KoreaCorrespondence: Young Taek Chung 325, Baekje-Daero, Wansan-Gu, Jeonju-si, Jeollabuk-do, Republic of KoreaTel +82 63 277 2774Email ytchungc@hanmail.netPurpose: To report 12-month results of small incision lenticule extraction (SMILE) in the treatment of myopia with corneal guttae (CG).Methods: We conducted a retrospective analysis of 12 eyes from six patients who had preoperative CG without clinical sign of Fuchs’ endothelial corneal dystrophy (FECD) and had SMILE for correction of myopia. Preoperative and 12-month postoperative measurements included uncorrected distance visual acuity (UDVA), spherical equivalent (SE), endothelial cell density (ECD), the coefficient of variation (CV), the percentage of hexagonal cells (HEX), and central corneal thickness (CCT). The changes in ECD, CV, HEX, and CCT after SMILE were subjected to statistical analysis.Results: Twelve months postoperatively, the mean SE was − 0.10 ± 0.32 D and all eyes had a UDVA of 0 logMAR or better. No eyes developed corneal edema or other complication during the follow-up period. There were no significant changes in the ECD, CV, or HEX at 12 months (all p> 0.05).Conclusion: SMILE yielded improvement in visual acuity and no adverse effects to corneal endothelial cells were found when correcting myopia or myopic astigmatism in patients with CG. However, studies with a greater number of patients and longer follow-up periods are needed to establish the long-term outcomes and safety.Keywords: small incision lenticule extraction, SMILE, corneal guttae, Fuchs’ endothelial corneal dystrophy
format	article
author	Kim BK Chung YT
author_facet	Kim BK Chung YT
author_sort	Kim BK
title	Small Incision Lenticule Extraction (SMILE) in Patients with Corneal Guttae
title_short	Small Incision Lenticule Extraction (SMILE) in Patients with Corneal Guttae
title_full	Small Incision Lenticule Extraction (SMILE) in Patients with Corneal Guttae
title_fullStr	Small Incision Lenticule Extraction (SMILE) in Patients with Corneal Guttae
title_full_unstemmed	Small Incision Lenticule Extraction (SMILE) in Patients with Corneal Guttae
title_sort	small incision lenticule extraction (smile) in patients with corneal guttae
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/14c32d078e0e49c796f83b05841d635a
work_keys_str_mv	AT kimbk smallincisionlenticuleextractionsmileinpatientswithcornealguttae AT chungyt smallincisionlenticuleextractionsmileinpatientswithcornealguttae
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Small Incision Lenticule Extraction (SMILE) in Patients with Corneal Guttae

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