Middle eastern genetic legacy in the paternal and maternal gene pools of Chuetas

Abstract Chuetas are a group of descendants of Majorcan Crypto-Jews (Balearic Islands, Spain) who were socially stigmatized and segregated by their Majorcan neighbours until recently; generating a community that, although after the seventeenth century no longer contained Judaic religious elements, m...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	J. F. Ferragut, C. Ramon, J. A. Castro, A. Amorim, L. Alvarez, A. Picornell
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/14c6aa6991964b669ff20a59bd5d0c88
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:14c6aa6991964b669ff20a59bd5d0c88
record_format	dspace
spelling	oai:doaj.org-article:14c6aa6991964b669ff20a59bd5d0c882021-12-02T16:18:06ZMiddle eastern genetic legacy in the paternal and maternal gene pools of Chuetas10.1038/s41598-020-78487-92045-2322https://doaj.org/article/14c6aa6991964b669ff20a59bd5d0c882020-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-78487-9https://doaj.org/toc/2045-2322Abstract Chuetas are a group of descendants of Majorcan Crypto-Jews (Balearic Islands, Spain) who were socially stigmatized and segregated by their Majorcan neighbours until recently; generating a community that, although after the seventeenth century no longer contained Judaic religious elements, maintained strong group cohesion, Jewishness consciousness, and endogamy. Collective memory fixed 15 surnames as a most important defining element of Chueta families. Previous studies demonstrated Chuetas were a differentiated population, with a considerable proportion of their original genetic make-up. Genetic data of Y-chromosome polymorphism and mtDNA control region showed, in Chuetas’ paternal lineages, high prevalence of haplogroups J2-M172 (33%) and J1-M267 (18%). In maternal lineages, the Chuetas hallmark is the presence of a new sub-branching of the rare haplogroup R0a2m as their modal haplogroup (21%). Genetic diversity in both Y-chromosome and mtDNA indicates the Chueta community has managed to avoid the expected heterogeneity decrease in their gene pool after centuries of isolation and inbreeding. Moreover, the composition of their uniparentally transmitted lineages demonstrates a remarkable signature of Middle Eastern ancestry—despite some degree of host admixture—confirming Chuetas have retained over the centuries a considerable degree of ancestral genetic signature along with the cultural memory of their Jewish origin.J. F. FerragutC. RamonJ. A. CastroA. AmorimL. AlvarezA. PicornellNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q J. F. Ferragut C. Ramon J. A. Castro A. Amorim L. Alvarez A. Picornell Middle eastern genetic legacy in the paternal and maternal gene pools of Chuetas
description	Abstract Chuetas are a group of descendants of Majorcan Crypto-Jews (Balearic Islands, Spain) who were socially stigmatized and segregated by their Majorcan neighbours until recently; generating a community that, although after the seventeenth century no longer contained Judaic religious elements, maintained strong group cohesion, Jewishness consciousness, and endogamy. Collective memory fixed 15 surnames as a most important defining element of Chueta families. Previous studies demonstrated Chuetas were a differentiated population, with a considerable proportion of their original genetic make-up. Genetic data of Y-chromosome polymorphism and mtDNA control region showed, in Chuetas’ paternal lineages, high prevalence of haplogroups J2-M172 (33%) and J1-M267 (18%). In maternal lineages, the Chuetas hallmark is the presence of a new sub-branching of the rare haplogroup R0a2m as their modal haplogroup (21%). Genetic diversity in both Y-chromosome and mtDNA indicates the Chueta community has managed to avoid the expected heterogeneity decrease in their gene pool after centuries of isolation and inbreeding. Moreover, the composition of their uniparentally transmitted lineages demonstrates a remarkable signature of Middle Eastern ancestry—despite some degree of host admixture—confirming Chuetas have retained over the centuries a considerable degree of ancestral genetic signature along with the cultural memory of their Jewish origin.
format	article
author	J. F. Ferragut C. Ramon J. A. Castro A. Amorim L. Alvarez A. Picornell
author_facet	J. F. Ferragut C. Ramon J. A. Castro A. Amorim L. Alvarez A. Picornell
author_sort	J. F. Ferragut
title	Middle eastern genetic legacy in the paternal and maternal gene pools of Chuetas
title_short	Middle eastern genetic legacy in the paternal and maternal gene pools of Chuetas
title_full	Middle eastern genetic legacy in the paternal and maternal gene pools of Chuetas
title_fullStr	Middle eastern genetic legacy in the paternal and maternal gene pools of Chuetas
title_full_unstemmed	Middle eastern genetic legacy in the paternal and maternal gene pools of Chuetas
title_sort	middle eastern genetic legacy in the paternal and maternal gene pools of chuetas
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/14c6aa6991964b669ff20a59bd5d0c88
work_keys_str_mv	AT jfferragut middleeasterngeneticlegacyinthepaternalandmaternalgenepoolsofchuetas AT cramon middleeasterngeneticlegacyinthepaternalandmaternalgenepoolsofchuetas AT jacastro middleeasterngeneticlegacyinthepaternalandmaternalgenepoolsofchuetas AT aamorim middleeasterngeneticlegacyinthepaternalandmaternalgenepoolsofchuetas AT lalvarez middleeasterngeneticlegacyinthepaternalandmaternalgenepoolsofchuetas AT apicornell middleeasterngeneticlegacyinthepaternalandmaternalgenepoolsofchuetas
_version_	1718384155760263168

Middle eastern genetic legacy in the paternal and maternal gene pools of Chuetas

Ejemplares similares