The protease inhibitor alpha-2-macroglobulin-like-1 is the p170 antigen recognized by paraneoplastic pemphigus autoantibodies in human.
<h4>Background</h4>Paraneoplastic pemphigus (PNP) is a devastating autoimmune blistering disease, involving mucocutaneous and internal organs, and associated with underlying neoplasms. PNP is characterized by the production of autoantibodies targeting proteins of the plakin and cadherin...
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Main Authors: | Isabelle Schepens, Fabienne Jaunin, Nadja Begre, Ursula Läderach, Katrin Marcus, Takashi Hashimoto, Bertrand Favre, Luca Borradori |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2010
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Online Access: | https://doaj.org/article/14cb1e83950043eda1b12d1e32f82835 |
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