Brittle cornea syndrome: current perspectives

Andrew Walkden,1,2 Emma Burkitt-Wright,3,4 Leon Au1,21Manchester Royal Eye Hospital, Manchester University Foundation Trust, Manchester, UK; 2Medical Academic Health Sciences Centre, University of Manchester, UK; 3Genetic Medicine, Institute of Human Development, Faculty of Medical and Human Science...

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Autores principales:	Walkden A, Burkitt-Wright E, Au L
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	Brittle Cornea Syndrome Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/14d0fa5eb1c94022ba73f43a4f3bbd68
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spelling	oai:doaj.org-article:14d0fa5eb1c94022ba73f43a4f3bbd682021-12-02T07:25:14ZBrittle cornea syndrome: current perspectives1177-5483https://doaj.org/article/14d0fa5eb1c94022ba73f43a4f3bbd682019-08-01T00:00:00Zhttps://www.dovepress.com/brittle-cornea-sydrome-current-perspectives-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Andrew Walkden,1,2 Emma Burkitt-Wright,3,4 Leon Au1,21Manchester Royal Eye Hospital, Manchester University Foundation Trust, Manchester, UK; 2Medical Academic Health Sciences Centre, University of Manchester, UK; 3Genetic Medicine, Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK; 4Genetic Medicine, St Mary’s Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UKAbstract: Brittle cornea syndrome (BCS) is a rare autosomal recessive connective tissue disorder characterised by severe corneal thinning, with the major ocular risk being spontaneous ocular perforation due to progressive stromal thinning and ectasia. It is a complex condition with limited treatment options. The purpose of this review is to highlight the difficulties associated with the condition and examine the available published evidence with regards to management.Keywords: brittle Cornea, spontaneous corneal perforation, corneal ectasiaWalkden ABurkitt-Wright EAu LDove Medical PressarticleBrittle Cornea SyndromeOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 13, Pp 1511-1516 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Brittle Cornea Syndrome Ophthalmology RE1-994
spellingShingle	Brittle Cornea Syndrome Ophthalmology RE1-994 Walkden A Burkitt-Wright E Au L Brittle cornea syndrome: current perspectives
description	Andrew Walkden,1,2 Emma Burkitt-Wright,3,4 Leon Au1,21Manchester Royal Eye Hospital, Manchester University Foundation Trust, Manchester, UK; 2Medical Academic Health Sciences Centre, University of Manchester, UK; 3Genetic Medicine, Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK; 4Genetic Medicine, St Mary’s Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UKAbstract: Brittle cornea syndrome (BCS) is a rare autosomal recessive connective tissue disorder characterised by severe corneal thinning, with the major ocular risk being spontaneous ocular perforation due to progressive stromal thinning and ectasia. It is a complex condition with limited treatment options. The purpose of this review is to highlight the difficulties associated with the condition and examine the available published evidence with regards to management.Keywords: brittle Cornea, spontaneous corneal perforation, corneal ectasia
format	article
author	Walkden A Burkitt-Wright E Au L
author_facet	Walkden A Burkitt-Wright E Au L
author_sort	Walkden A
title	Brittle cornea syndrome: current perspectives
title_short	Brittle cornea syndrome: current perspectives
title_full	Brittle cornea syndrome: current perspectives
title_fullStr	Brittle cornea syndrome: current perspectives
title_full_unstemmed	Brittle cornea syndrome: current perspectives
title_sort	brittle cornea syndrome: current perspectives
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/14d0fa5eb1c94022ba73f43a4f3bbd68
work_keys_str_mv	AT walkdena brittlecorneasyndromecurrentperspectives AT burkittwrighte brittlecorneasyndromecurrentperspectives AT aul brittlecorneasyndromecurrentperspectives
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Brittle cornea syndrome: current perspectives

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