Post-surgical adhesions are triggered by calcium-dependent membrane bridges between mesothelial surfaces
Surgical adhesions are organ-joining bands of scar tissue that remain clinically untreatable. Here, the authors show that adhesions are formed through expansive mesothelial membrane bridges, and that blocking these with small molecules prevents formation of adhesions in mice.
Guardado en:
Autores principales: | Adrian Fischer, Tim Koopmans, Pushkar Ramesh, Simon Christ, Maximilian Strunz, Juliane Wannemacher, Michaela Aichler, Annette Feuchtinger, Axel Walch, Meshal Ansari, Fabian J. Theis, Kenji Schorpp, Kamyar Hadian, Philipp-Alexander Neumann, Herbert B. Schiller, Yuval Rinkevich |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/14eab87dfd66492c8aa804c34480c9bf |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
An in vivo high-throughput screening for riboswitch ligands using a reverse reporter gene system
por: Marion Kirchner, et al.
Publicado: (2017) -
Injury triggers fascia fibroblast collective cell migration to drive scar formation through N-cadherin
por: Dongsheng Jiang, et al.
Publicado: (2020) -
A rare case of an intramyocardial mesothelial inclusion cyst
por: Shehani Alwis, et al.
Publicado: (2021) -
Mesothelial-to-Mesenchymal Transition and Exosomes in Peritoneal Metastasis of Ovarian Cancer
por: Lucía Pascual-Antón, et al.
Publicado: (2021) -
Folliculin haploinsufficiency causes cellular dysfunction of pleural mesothelial cells
por: Shouichi Okamoto, et al.
Publicado: (2021)