Positive Association Between Plasma Aldosterone Concentration and White Matter Lesions in Patients With Hypertension

Positive Association Between Plasma Aldosterone Concentration and White Matter Lesions in Patients With Hypertension

Background and ObjectiveWhite matter lesions (WMLs) are imaging changes in MRI of cerebral small vessel disease associated with vascular risk factors, increasing the risk of dementia, depression, and stroke. Aldosterone (ALD) or activation of mineralocorticoid receptor (MR) causes cerebrovascular in...

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Bibliographic Details
Main Authors: Yujuan Yuan, Nanfang Li, Yan Liu, Qing Zhu, Mulalibieke Heizhati, Weiwei Zhang, Xiaoguang Yao, Deilian Zhang, Qin Luo, Menghui Wang, Guijuan Chang, Mei Cao, Keming Zhou, Lei Wang, Junli Hu, Nuerguli Maimaiti
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
plasma aldosterone concentration (PAC)
white matter lesions (WMLs)
hypertension
cerebral small vessel disease
plasma renin activity (PRA)
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
Online Access:https://doaj.org/article/14ece4170aae43fca901555d7b8dc08c
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