Deep Membrane Proteome Profiling Reveals Overexpression of Prostate-Specific Membrane Antigen (PSMA) in High-Risk Human Paraganglioma and Pheochromocytoma, Suggesting New Theranostic Opportunity

Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors arising from chromaffin cells of adrenal medulla or sympathetic or parasympathetic paraganglia, respectively. To identify new therapeutic targets, we performed a detailed membrane-focused proteomic analysis of five human par...

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Auteurs principaux: Ondrej Vit, Mayank Patel, Zdenek Musil, Igor Hartmann, Zdenek Frysak, Markku Miettinen, Karel Pacak, Jiri Petrak
Format: article
Langue:EN
Publié: MDPI AG 2021
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Accès en ligne:https://doaj.org/article/14efd9a646c84c37b9eeece5bb72d5b5
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