Effect of Multiple Sclerosis and Its Treatments on Male Fertility: Cues for Future Research

Multiple sclerosis is a chronic disease that may lead to different types of symptoms and disabilities. with the better quality of life and decreased disability due to early diagnosis and the availability of disease-modifying therapies (DMTs), the treating physician is increasingly asked to counsel p...

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Autores principales:	Claudia Massarotti, Elvira Sbragia, Irene Gazzo, Sara Stigliani, Matilde Inglese, Paola Anserini
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	multiple sclerosis male fertility sperm analysis gonadotoxicity reproduction and chronic diseases fertility and multiple sclerosis Medicine R
Acceso en línea:	https://doaj.org/article/14f09a689b404ddca2ffdb115eab314b
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spelling	oai:doaj.org-article:14f09a689b404ddca2ffdb115eab314b2021-11-25T18:02:27ZEffect of Multiple Sclerosis and Its Treatments on Male Fertility: Cues for Future Research10.3390/jcm102254012077-0383https://doaj.org/article/14f09a689b404ddca2ffdb115eab314b2021-11-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/22/5401https://doaj.org/toc/2077-0383Multiple sclerosis is a chronic disease that may lead to different types of symptoms and disabilities. with the better quality of life and decreased disability due to early diagnosis and the availability of disease-modifying therapies (DMTs), the treating physician is increasingly asked to counsel patients on its effects on fertility and reproduction. In particular, reproductive issues are still scarcely studied and discussed in men. Among the still open questions are the following: (a) Does multiple sclerosis cause infertility per sè? (b) Is multiple sclerosis correlated with conditions that increase the risk of infertility? (c) Do DMTs or other therapies for multiple sclerosis impact gonadal function in men? The aim of this review is to provide an overview on the available literature data about the reproductive issues unique to men with multiple sclerosis, underlining the numerous areas where evidence is lacking and, therefore, the priorities for future research.Claudia MassarottiElvira SbragiaIrene GazzoSara StiglianiMatilde InglesePaola AnseriniMDPI AGarticlemultiple sclerosismale fertilitysperm analysisgonadotoxicityreproduction and chronic diseasesfertility and multiple sclerosisMedicineRENJournal of Clinical Medicine, Vol 10, Iss 5401, p 5401 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	multiple sclerosis male fertility sperm analysis gonadotoxicity reproduction and chronic diseases fertility and multiple sclerosis Medicine R
spellingShingle	multiple sclerosis male fertility sperm analysis gonadotoxicity reproduction and chronic diseases fertility and multiple sclerosis Medicine R Claudia Massarotti Elvira Sbragia Irene Gazzo Sara Stigliani Matilde Inglese Paola Anserini Effect of Multiple Sclerosis and Its Treatments on Male Fertility: Cues for Future Research
description	Multiple sclerosis is a chronic disease that may lead to different types of symptoms and disabilities. with the better quality of life and decreased disability due to early diagnosis and the availability of disease-modifying therapies (DMTs), the treating physician is increasingly asked to counsel patients on its effects on fertility and reproduction. In particular, reproductive issues are still scarcely studied and discussed in men. Among the still open questions are the following: (a) Does multiple sclerosis cause infertility per sè? (b) Is multiple sclerosis correlated with conditions that increase the risk of infertility? (c) Do DMTs or other therapies for multiple sclerosis impact gonadal function in men? The aim of this review is to provide an overview on the available literature data about the reproductive issues unique to men with multiple sclerosis, underlining the numerous areas where evidence is lacking and, therefore, the priorities for future research.
format	article
author	Claudia Massarotti Elvira Sbragia Irene Gazzo Sara Stigliani Matilde Inglese Paola Anserini
author_facet	Claudia Massarotti Elvira Sbragia Irene Gazzo Sara Stigliani Matilde Inglese Paola Anserini
author_sort	Claudia Massarotti
title	Effect of Multiple Sclerosis and Its Treatments on Male Fertility: Cues for Future Research
title_short	Effect of Multiple Sclerosis and Its Treatments on Male Fertility: Cues for Future Research
title_full	Effect of Multiple Sclerosis and Its Treatments on Male Fertility: Cues for Future Research
title_fullStr	Effect of Multiple Sclerosis and Its Treatments on Male Fertility: Cues for Future Research
title_full_unstemmed	Effect of Multiple Sclerosis and Its Treatments on Male Fertility: Cues for Future Research
title_sort	effect of multiple sclerosis and its treatments on male fertility: cues for future research
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/14f09a689b404ddca2ffdb115eab314b
work_keys_str_mv	AT claudiamassarotti effectofmultiplesclerosisanditstreatmentsonmalefertilitycuesforfutureresearch AT elvirasbragia effectofmultiplesclerosisanditstreatmentsonmalefertilitycuesforfutureresearch AT irenegazzo effectofmultiplesclerosisanditstreatmentsonmalefertilitycuesforfutureresearch AT sarastigliani effectofmultiplesclerosisanditstreatmentsonmalefertilitycuesforfutureresearch AT matildeinglese effectofmultiplesclerosisanditstreatmentsonmalefertilitycuesforfutureresearch AT paolaanserini effectofmultiplesclerosisanditstreatmentsonmalefertilitycuesforfutureresearch
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Effect of Multiple Sclerosis and Its Treatments on Male Fertility: Cues for Future Research

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