Cdk1 activity acts as a quantitative platform for coordinating cell cycle progression with periodic transcription
Cell proliferation is regulated by cyclin-dependent kinases (Cdks) and relies on periodic gene cluster expression according to cell cycle phases. Here the authors use a synthetic regulatable Cdk1 module to demonstrate that periodic expression is governed by quantitative changes in Cdk1 activity.
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Nature Portfolio
2016
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oai:doaj.org-article:14fd02f2836143969ca0e6808a740f352021-12-02T16:49:25ZCdk1 activity acts as a quantitative platform for coordinating cell cycle progression with periodic transcription10.1038/ncomms111612041-1723https://doaj.org/article/14fd02f2836143969ca0e6808a740f352016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11161https://doaj.org/toc/2041-1723Cell proliferation is regulated by cyclin-dependent kinases (Cdks) and relies on periodic gene cluster expression according to cell cycle phases. Here the authors use a synthetic regulatable Cdk1 module to demonstrate that periodic expression is governed by quantitative changes in Cdk1 activity.Gabor BanyaiFeriel BaïdiDamien CoudreuseZsolt SzilagyiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016) |
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Science Q Gabor Banyai Feriel Baïdi Damien Coudreuse Zsolt Szilagyi Cdk1 activity acts as a quantitative platform for coordinating cell cycle progression with periodic transcription |
description |
Cell proliferation is regulated by cyclin-dependent kinases (Cdks) and relies on periodic gene cluster expression according to cell cycle phases. Here the authors use a synthetic regulatable Cdk1 module to demonstrate that periodic expression is governed by quantitative changes in Cdk1 activity. |
format |
article |
author |
Gabor Banyai Feriel Baïdi Damien Coudreuse Zsolt Szilagyi |
author_facet |
Gabor Banyai Feriel Baïdi Damien Coudreuse Zsolt Szilagyi |
author_sort |
Gabor Banyai |
title |
Cdk1 activity acts as a quantitative platform for coordinating cell cycle progression with periodic transcription |
title_short |
Cdk1 activity acts as a quantitative platform for coordinating cell cycle progression with periodic transcription |
title_full |
Cdk1 activity acts as a quantitative platform for coordinating cell cycle progression with periodic transcription |
title_fullStr |
Cdk1 activity acts as a quantitative platform for coordinating cell cycle progression with periodic transcription |
title_full_unstemmed |
Cdk1 activity acts as a quantitative platform for coordinating cell cycle progression with periodic transcription |
title_sort |
cdk1 activity acts as a quantitative platform for coordinating cell cycle progression with periodic transcription |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/14fd02f2836143969ca0e6808a740f35 |
work_keys_str_mv |
AT gaborbanyai cdk1activityactsasaquantitativeplatformforcoordinatingcellcycleprogressionwithperiodictranscription AT ferielbaidi cdk1activityactsasaquantitativeplatformforcoordinatingcellcycleprogressionwithperiodictranscription AT damiencoudreuse cdk1activityactsasaquantitativeplatformforcoordinatingcellcycleprogressionwithperiodictranscription AT zsoltszilagyi cdk1activityactsasaquantitativeplatformforcoordinatingcellcycleprogressionwithperiodictranscription |
_version_ |
1718383319053238272 |