Cdk1 activity acts as a quantitative platform for coordinating cell cycle progression with periodic transcription

Cell proliferation is regulated by cyclin-dependent kinases (Cdks) and relies on periodic gene cluster expression according to cell cycle phases. Here the authors use a synthetic regulatable Cdk1 module to demonstrate that periodic expression is governed by quantitative changes in Cdk1 activity.

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Autores principales: Gabor Banyai, Feriel Baïdi, Damien Coudreuse, Zsolt Szilagyi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/14fd02f2836143969ca0e6808a740f35
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spelling oai:doaj.org-article:14fd02f2836143969ca0e6808a740f352021-12-02T16:49:25ZCdk1 activity acts as a quantitative platform for coordinating cell cycle progression with periodic transcription10.1038/ncomms111612041-1723https://doaj.org/article/14fd02f2836143969ca0e6808a740f352016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11161https://doaj.org/toc/2041-1723Cell proliferation is regulated by cyclin-dependent kinases (Cdks) and relies on periodic gene cluster expression according to cell cycle phases. Here the authors use a synthetic regulatable Cdk1 module to demonstrate that periodic expression is governed by quantitative changes in Cdk1 activity.Gabor BanyaiFeriel BaïdiDamien CoudreuseZsolt SzilagyiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Gabor Banyai
Feriel Baïdi
Damien Coudreuse
Zsolt Szilagyi
Cdk1 activity acts as a quantitative platform for coordinating cell cycle progression with periodic transcription
description Cell proliferation is regulated by cyclin-dependent kinases (Cdks) and relies on periodic gene cluster expression according to cell cycle phases. Here the authors use a synthetic regulatable Cdk1 module to demonstrate that periodic expression is governed by quantitative changes in Cdk1 activity.
format article
author Gabor Banyai
Feriel Baïdi
Damien Coudreuse
Zsolt Szilagyi
author_facet Gabor Banyai
Feriel Baïdi
Damien Coudreuse
Zsolt Szilagyi
author_sort Gabor Banyai
title Cdk1 activity acts as a quantitative platform for coordinating cell cycle progression with periodic transcription
title_short Cdk1 activity acts as a quantitative platform for coordinating cell cycle progression with periodic transcription
title_full Cdk1 activity acts as a quantitative platform for coordinating cell cycle progression with periodic transcription
title_fullStr Cdk1 activity acts as a quantitative platform for coordinating cell cycle progression with periodic transcription
title_full_unstemmed Cdk1 activity acts as a quantitative platform for coordinating cell cycle progression with periodic transcription
title_sort cdk1 activity acts as a quantitative platform for coordinating cell cycle progression with periodic transcription
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/14fd02f2836143969ca0e6808a740f35
work_keys_str_mv AT gaborbanyai cdk1activityactsasaquantitativeplatformforcoordinatingcellcycleprogressionwithperiodictranscription
AT ferielbaidi cdk1activityactsasaquantitativeplatformforcoordinatingcellcycleprogressionwithperiodictranscription
AT damiencoudreuse cdk1activityactsasaquantitativeplatformforcoordinatingcellcycleprogressionwithperiodictranscription
AT zsoltszilagyi cdk1activityactsasaquantitativeplatformforcoordinatingcellcycleprogressionwithperiodictranscription
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