Kaposi’s Sarcoma-Associated Herpesvirus Increases PD-L1 and Proinflammatory Cytokine Expression in Human Monocytes

Kaposi’s Sarcoma-Associated Herpesvirus Increases PD-L1 and Proinflammatory Cytokine Expression in Human Monocytes

ABSTRACT Kaposi’s sarcoma-associated herpesvirus (KSHV) is associated with the human malignancy Kaposi’s sarcoma and the lymphoproliferative disorders primary effusion lymphoma and multicentric Castleman’s disease. KSHV establishes lytic infection of monocytes in vivo, which may represent an importa...

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Bibliographic Details
Main Authors: Kurtis M. Host, Sarah R. Jacobs, John A. West, Zhigang Zhang, Lindsey M. Costantini, Charles M. Stopford, Dirk P. Dittmer, Blossom Damania
Format: article
Language:EN
Published: American Society for Microbiology 2017
Subjects:
Kaposi’s sarcoma-associated herpesvirus
PD-1
PD-L1
human herpesvirus
innate immunity
Microbiology
QR1-502
Online Access:https://doaj.org/article/1500b2e7ba7f4ffa9862cea2aac65852
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https://doaj.org/article/1500b2e7ba7f4ffa9862cea2aac65852

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