Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability

SOCS3 is an important negative feedback inhibitor of JAK–STAT-mediated cytokine signalling. Here the authors implicate cavin-1 — an essential component of caveolae — in the recruitment of SOCS3 to the plasma membrane to prevent sustained cytokine receptor signalling.

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Autores principales:	Jamie J. L. Williams, Nasser Alotaiq, William Mullen, Richard Burchmore, Libin Liu, George S. Baillie, Fred Schaper, Paul F. Pilch, Timothy M. Palmer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/150955b131d248018bd4158e8688ea0e
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spelling	oai:doaj.org-article:150955b131d248018bd4158e8688ea0e2021-12-02T14:40:05ZInteraction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability10.1038/s41467-017-02585-y2041-1723https://doaj.org/article/150955b131d248018bd4158e8688ea0e2018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02585-yhttps://doaj.org/toc/2041-1723SOCS3 is an important negative feedback inhibitor of JAK–STAT-mediated cytokine signalling. Here the authors implicate cavin-1 — an essential component of caveolae — in the recruitment of SOCS3 to the plasma membrane to prevent sustained cytokine receptor signalling.Jamie J. L. WilliamsNasser AlotaiqWilliam MullenRichard BurchmoreLibin LiuGeorge S. BaillieFred SchaperPaul F. PilchTimothy M. PalmerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jamie J. L. Williams Nasser Alotaiq William Mullen Richard Burchmore Libin Liu George S. Baillie Fred Schaper Paul F. Pilch Timothy M. Palmer Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability
description	SOCS3 is an important negative feedback inhibitor of JAK–STAT-mediated cytokine signalling. Here the authors implicate cavin-1 — an essential component of caveolae — in the recruitment of SOCS3 to the plasma membrane to prevent sustained cytokine receptor signalling.
format	article
author	Jamie J. L. Williams Nasser Alotaiq William Mullen Richard Burchmore Libin Liu George S. Baillie Fred Schaper Paul F. Pilch Timothy M. Palmer
author_facet	Jamie J. L. Williams Nasser Alotaiq William Mullen Richard Burchmore Libin Liu George S. Baillie Fred Schaper Paul F. Pilch Timothy M. Palmer
author_sort	Jamie J. L. Williams
title	Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability
title_short	Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability
title_full	Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability
title_fullStr	Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability
title_full_unstemmed	Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability
title_sort	interaction of suppressor of cytokine signalling 3 with cavin-1 links socs3 function and cavin-1 stability
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/150955b131d248018bd4158e8688ea0e
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Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability

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