The Landscape of Phenotypic and Transcriptional Responses to Ciprofloxacin in <named-content content-type="genus-species">Acinetobacter baumannii</named-content>: Acquired Resistance Alleles Modulate Drug-Induced SOS Response and Prophage Replication
ABSTRACT The emergence of fluoroquinolone resistance in nosocomial pathogens has restricted the clinical efficacy of this antibiotic class. In Acinetobacter baumannii, the majority of clinical isolates now show high-level resistance due to mutations in gyrA (DNA gyrase) and parC (topoisomerase IV [t...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2019
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| Subjects: | |
| Online Access: | https://doaj.org/article/1509ec34b30745a8b0fd843a51447f90 |
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