The kallikrein–kinin pathway as a mechanism for auto-control of brown adipose tissue activity

Brown adipose tissue, known produce heat by metabolizing fat, is also secretes molecules capable of communicating with other organs. Here the authors show that brown adipose tissue secretes kininogen, a component of heat system regulation, that provides auto-regulatory inhibitory signaling in brown...

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Autores principales: Marion Peyrou, Rubén Cereijo, Tania Quesada-López, Laura Campderrós, Aleix Gavaldà-Navarro, Laura Liñares-Pose, Elena Kaschina, Thomas Unger, Miguel López, Marta Giralt, Francesc Villarroya
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/150ca23506ff4dd1a06c23947991322f
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Sumario:Brown adipose tissue, known produce heat by metabolizing fat, is also secretes molecules capable of communicating with other organs. Here the authors show that brown adipose tissue secretes kininogen, a component of heat system regulation, that provides auto-regulatory inhibitory signaling in brown adipose tissue.