An experimental-mathematical approach to predict tumor cell growth as a function of glucose availability in breast cancer cell lines.

We present the development and validation of a mathematical model that predicts how glucose dynamics influence metabolism and therefore tumor cell growth. Glucose, the starting material for glycolysis, has a fundamental influence on tumor cell growth. We employed time-resolved microscopy to track th...

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Bibliographic Details
Main Authors: Jianchen Yang, Jack Virostko, David A Hormuth, Junyan Liu, Amy Brock, Jeanne Kowalski, Thomas E Yankeelov
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
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Online Access:https://doaj.org/article/150d9accb7674f75a65bd44e8bc827b6
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