Scutoids are a geometrical solution to three-dimensional packing of epithelia

Cell arrangement in the plane of epithelia is well studied, but its three-dimensional packing is largely unknown. Here the authors model curved epithelia and predict that cells adopt a geometrical shape they call “scutoid”, resulting in different apical and basal neighbours, and confirm the presence...

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Autores principales: Pedro Gómez-Gálvez, Pablo Vicente-Munuera, Antonio Tagua, Cristina Forja, Ana M. Castro, Marta Letrán, Andrea Valencia-Expósito, Clara Grima, Marina Bermúdez-Gallardo, Óscar Serrano-Pérez-Higueras, Florencia Cavodeassi, Sol Sotillos, María D. Martín-Bermudo, Alberto Márquez, Javier Buceta, Luis M. Escudero
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/15120a6bf3ff476aacd098f151c1993e
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spelling oai:doaj.org-article:15120a6bf3ff476aacd098f151c1993e2021-12-02T14:39:28ZScutoids are a geometrical solution to three-dimensional packing of epithelia10.1038/s41467-018-05376-12041-1723https://doaj.org/article/15120a6bf3ff476aacd098f151c1993e2018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05376-1https://doaj.org/toc/2041-1723Cell arrangement in the plane of epithelia is well studied, but its three-dimensional packing is largely unknown. Here the authors model curved epithelia and predict that cells adopt a geometrical shape they call “scutoid”, resulting in different apical and basal neighbours, and confirm the presence of scutoids in curved tissues.Pedro Gómez-GálvezPablo Vicente-MunueraAntonio TaguaCristina ForjaAna M. CastroMarta LetránAndrea Valencia-ExpósitoClara GrimaMarina Bermúdez-GallardoÓscar Serrano-Pérez-HiguerasFlorencia CavodeassiSol SotillosMaría D. Martín-BermudoAlberto MárquezJavier BucetaLuis M. EscuderoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Pedro Gómez-Gálvez
Pablo Vicente-Munuera
Antonio Tagua
Cristina Forja
Ana M. Castro
Marta Letrán
Andrea Valencia-Expósito
Clara Grima
Marina Bermúdez-Gallardo
Óscar Serrano-Pérez-Higueras
Florencia Cavodeassi
Sol Sotillos
María D. Martín-Bermudo
Alberto Márquez
Javier Buceta
Luis M. Escudero
Scutoids are a geometrical solution to three-dimensional packing of epithelia
description Cell arrangement in the plane of epithelia is well studied, but its three-dimensional packing is largely unknown. Here the authors model curved epithelia and predict that cells adopt a geometrical shape they call “scutoid”, resulting in different apical and basal neighbours, and confirm the presence of scutoids in curved tissues.
format article
author Pedro Gómez-Gálvez
Pablo Vicente-Munuera
Antonio Tagua
Cristina Forja
Ana M. Castro
Marta Letrán
Andrea Valencia-Expósito
Clara Grima
Marina Bermúdez-Gallardo
Óscar Serrano-Pérez-Higueras
Florencia Cavodeassi
Sol Sotillos
María D. Martín-Bermudo
Alberto Márquez
Javier Buceta
Luis M. Escudero
author_facet Pedro Gómez-Gálvez
Pablo Vicente-Munuera
Antonio Tagua
Cristina Forja
Ana M. Castro
Marta Letrán
Andrea Valencia-Expósito
Clara Grima
Marina Bermúdez-Gallardo
Óscar Serrano-Pérez-Higueras
Florencia Cavodeassi
Sol Sotillos
María D. Martín-Bermudo
Alberto Márquez
Javier Buceta
Luis M. Escudero
author_sort Pedro Gómez-Gálvez
title Scutoids are a geometrical solution to three-dimensional packing of epithelia
title_short Scutoids are a geometrical solution to three-dimensional packing of epithelia
title_full Scutoids are a geometrical solution to three-dimensional packing of epithelia
title_fullStr Scutoids are a geometrical solution to three-dimensional packing of epithelia
title_full_unstemmed Scutoids are a geometrical solution to three-dimensional packing of epithelia
title_sort scutoids are a geometrical solution to three-dimensional packing of epithelia
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/15120a6bf3ff476aacd098f151c1993e
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