A transparent waveguide chip for versatile total internal reflection fluorescence-based microscopy and nanoscopy

Total internal reflection fluorescence microscopy typically relies on opaque optical waveguides, compatible only with upright microscopes. Here, a versatile approach is reported that uses CMOS-compatible transparent chips, demonstrated for the imaging of synthetic and biological samples, including s...

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Autores principales:	Anish Priyadarshi, Firehun Tsige Dullo, Deanna Lynn Wolfson, Azeem Ahmad, Nikhil Jayakumar, Vishesh Dubey, Jean-Claude Tinguely, Balpreet Singh Ahluwalia, Ganapathy Senthil Murugan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Materials of engineering and construction. Mechanics of materials TA401-492
Acceso en línea:	https://doaj.org/article/151402563e47422c99e9146c7e4fe541
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spelling	oai:doaj.org-article:151402563e47422c99e9146c7e4fe5412021-12-02T15:10:39ZA transparent waveguide chip for versatile total internal reflection fluorescence-based microscopy and nanoscopy10.1038/s43246-021-00192-52662-4443https://doaj.org/article/151402563e47422c99e9146c7e4fe5412021-08-01T00:00:00Zhttps://doi.org/10.1038/s43246-021-00192-5https://doaj.org/toc/2662-4443Total internal reflection fluorescence microscopy typically relies on opaque optical waveguides, compatible only with upright microscopes. Here, a versatile approach is reported that uses CMOS-compatible transparent chips, demonstrated for the imaging of synthetic and biological samples, including super-resolution applications.Anish PriyadarshiFirehun Tsige DulloDeanna Lynn WolfsonAzeem AhmadNikhil JayakumarVishesh DubeyJean-Claude TinguelyBalpreet Singh AhluwaliaGanapathy Senthil MuruganNature PortfolioarticleMaterials of engineering and construction. Mechanics of materialsTA401-492ENCommunications Materials, Vol 2, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Materials of engineering and construction. Mechanics of materials TA401-492
spellingShingle	Materials of engineering and construction. Mechanics of materials TA401-492 Anish Priyadarshi Firehun Tsige Dullo Deanna Lynn Wolfson Azeem Ahmad Nikhil Jayakumar Vishesh Dubey Jean-Claude Tinguely Balpreet Singh Ahluwalia Ganapathy Senthil Murugan A transparent waveguide chip for versatile total internal reflection fluorescence-based microscopy and nanoscopy
description	Total internal reflection fluorescence microscopy typically relies on opaque optical waveguides, compatible only with upright microscopes. Here, a versatile approach is reported that uses CMOS-compatible transparent chips, demonstrated for the imaging of synthetic and biological samples, including super-resolution applications.
format	article
author	Anish Priyadarshi Firehun Tsige Dullo Deanna Lynn Wolfson Azeem Ahmad Nikhil Jayakumar Vishesh Dubey Jean-Claude Tinguely Balpreet Singh Ahluwalia Ganapathy Senthil Murugan
author_facet	Anish Priyadarshi Firehun Tsige Dullo Deanna Lynn Wolfson Azeem Ahmad Nikhil Jayakumar Vishesh Dubey Jean-Claude Tinguely Balpreet Singh Ahluwalia Ganapathy Senthil Murugan
author_sort	Anish Priyadarshi
title	A transparent waveguide chip for versatile total internal reflection fluorescence-based microscopy and nanoscopy
title_short	A transparent waveguide chip for versatile total internal reflection fluorescence-based microscopy and nanoscopy
title_full	A transparent waveguide chip for versatile total internal reflection fluorescence-based microscopy and nanoscopy
title_fullStr	A transparent waveguide chip for versatile total internal reflection fluorescence-based microscopy and nanoscopy
title_full_unstemmed	A transparent waveguide chip for versatile total internal reflection fluorescence-based microscopy and nanoscopy
title_sort	transparent waveguide chip for versatile total internal reflection fluorescence-based microscopy and nanoscopy
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/151402563e47422c99e9146c7e4fe541
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A transparent waveguide chip for versatile total internal reflection fluorescence-based microscopy and nanoscopy

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