Connective tissue growth factor promotes chemotaxis of preosteoblasts through integrin α5 and Ras during tensile force-induced intramembranous osteogenesis

Abstract In vertebrates, new bone formation via intramembranous osteogenesis is a critical biological event for development, remodeling, and fracture healing of bones. Chemotaxis of osteoblast lineage cells is an essential cellular process in new bone formation. Connective tissue growth factor (CTGF...

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Autores principales: Wei Jiang, Nobuo Takeshita, Toshihiro Maeda, Chisumi Sogi, Toshihito Oyanagi, Seiji Kimura, Michiko Yoshida, Kiyo Sasaki, Arata Ito, Teruko Takano-Yamamoto
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/151c0e7d446247ac856f8c25541f48b1
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