Clinical experiences in fungal keratitis caused by Acremonium

Seong-Jae Kim,1,2 Yong-Wun Cho,1 Seong-Wook Seo,1,2 Sun-Joo Kim,2,3 Ji-Myong Yoo1,21Department of Ophthalmology, 2Gyeongsang Institute of Health Science, 3Department of Laboratory Medicine, Gyeongsang National University, College of Medicine, Jinju, KoreaPurpose: To report the predisposing risk fac...

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Autores principales:	Kim SJ, Cho YW, Seo SW, Yoo JM
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/152d4bafd8f947dc845d24905cde3602
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spelling	oai:doaj.org-article:152d4bafd8f947dc845d24905cde36022021-12-02T07:44:27ZClinical experiences in fungal keratitis caused by Acremonium1177-5483https://doaj.org/article/152d4bafd8f947dc845d24905cde36022014-01-01T00:00:00Zhttp://www.dovepress.com/clinical-experiences-in-fungal-keratitis-caused-by-acremonium-a15605https://doaj.org/toc/1177-5483 Seong-Jae Kim,1,2 Yong-Wun Cho,1 Seong-Wook Seo,1,2 Sun-Joo Kim,2,3 Ji-Myong Yoo1,21Department of Ophthalmology, 2Gyeongsang Institute of Health Science, 3Department of Laboratory Medicine, Gyeongsang National University, College of Medicine, Jinju, KoreaPurpose: To report the predisposing risk factors, clinical presentation, management, and therapeutic outcomes of fungal keratitis caused by Acremonium.Methods: This is a retrospective study of cases with Acremonium fungal keratitis that presented to our tertiary referral center between January 2006 and August 2012. Patient demographic and clinical details were determined and reported.Results: Five cases of fungal keratitis from Acremonium species were identified in five patients (three males, two females). The mean age of the patients was of 73.4±5.46 years, with a mean follow-up time of 124±72 days. All patients had a history of corneal trauma with vegetable matter. Four cases were unresponsive to initial treatment (0.2% fluconazole, 0.15% amphotericin B) and required topical 5% natamycin, and, in two out of five cases, topical 1% voriconazole.Conclusion: The most common risk factors for Acremonium fungal keratitis was ocular trauma. When a corneal lesion is found to be unresponsive to the initial treatment, we should consider adding or substituting topical natamycin or voriconazole for treatment.Keywords: Acremonium, fungal keratitis, natamycin, prognosis, voriconazoleKim SJCho YWSeo SWKim SJYoo JMDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2014, Iss default, Pp 283-287 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Kim SJ Cho YW Seo SW Kim SJ Yoo JM Clinical experiences in fungal keratitis caused by Acremonium
description	Seong-Jae Kim,1,2 Yong-Wun Cho,1 Seong-Wook Seo,1,2 Sun-Joo Kim,2,3 Ji-Myong Yoo1,21Department of Ophthalmology, 2Gyeongsang Institute of Health Science, 3Department of Laboratory Medicine, Gyeongsang National University, College of Medicine, Jinju, KoreaPurpose: To report the predisposing risk factors, clinical presentation, management, and therapeutic outcomes of fungal keratitis caused by Acremonium.Methods: This is a retrospective study of cases with Acremonium fungal keratitis that presented to our tertiary referral center between January 2006 and August 2012. Patient demographic and clinical details were determined and reported.Results: Five cases of fungal keratitis from Acremonium species were identified in five patients (three males, two females). The mean age of the patients was of 73.4±5.46 years, with a mean follow-up time of 124±72 days. All patients had a history of corneal trauma with vegetable matter. Four cases were unresponsive to initial treatment (0.2% fluconazole, 0.15% amphotericin B) and required topical 5% natamycin, and, in two out of five cases, topical 1% voriconazole.Conclusion: The most common risk factors for Acremonium fungal keratitis was ocular trauma. When a corneal lesion is found to be unresponsive to the initial treatment, we should consider adding or substituting topical natamycin or voriconazole for treatment.Keywords: Acremonium, fungal keratitis, natamycin, prognosis, voriconazole
format	article
author	Kim SJ Cho YW Seo SW Kim SJ Yoo JM
author_facet	Kim SJ Cho YW Seo SW Kim SJ Yoo JM
author_sort	Kim SJ
title	Clinical experiences in fungal keratitis caused by Acremonium
title_short	Clinical experiences in fungal keratitis caused by Acremonium
title_full	Clinical experiences in fungal keratitis caused by Acremonium
title_fullStr	Clinical experiences in fungal keratitis caused by Acremonium
title_full_unstemmed	Clinical experiences in fungal keratitis caused by Acremonium
title_sort	clinical experiences in fungal keratitis caused by acremonium
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/152d4bafd8f947dc845d24905cde3602
work_keys_str_mv	AT kimsj clinicalexperiencesinfungalkeratitiscausedbyacremonium AT choyw clinicalexperiencesinfungalkeratitiscausedbyacremonium AT seosw clinicalexperiencesinfungalkeratitiscausedbyacremonium AT kimsj clinicalexperiencesinfungalkeratitiscausedbyacremonium AT yoojm clinicalexperiencesinfungalkeratitiscausedbyacremonium
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Clinical experiences in fungal keratitis caused by Acremonium

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