Changes in Thyroid Hormones Levels and Metabolism in Dairy Cows around Calving

The hormonal activity of the thyroid gland has an important role in ruminants for the modulation of metabolic variables. In this study changes in thyroid hormones and biochemical parameters in dairy cows around calving were evaluated and the critical thyroid hormones thresholds for predicting the ri...

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Autores principales:	Fiore Enrico, Giambelluca Sonia, Morgante Massimo, Piccione Giuseppe, Vazzana Irene, Contiero Barbara, Orefice Tiziana, Arfuso Francesca, Gianesella Matteo
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2017
Materias:	dairy cow metabolism thyroid hormone transition period Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/15331a90f9024462ae4ad1635cb92ea5
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spelling	oai:doaj.org-article:15331a90f9024462ae4ad1635cb92ea52021-11-17T21:27:51ZChanges in Thyroid Hormones Levels and Metabolism in Dairy Cows around Calving1820-744810.1515/acve-2017-0026https://doaj.org/article/15331a90f9024462ae4ad1635cb92ea52017-09-01T00:00:00Zhttps://doi.org/10.1515/acve-2017-0026https://doaj.org/toc/1820-7448The hormonal activity of the thyroid gland has an important role in ruminants for the modulation of metabolic variables. In this study changes in thyroid hormones and biochemical parameters in dairy cows around calving were evaluated and the critical thyroid hormones thresholds for predicting the risk of ketosis were estimated. Blood samples were collected from 82 dairy cows at 5±3 days pre-partum and 5±3 days postpartum. Serum values of triiodothyronine (T3), thyroxine (T4), thyroid-stimulating hormone (TSH), non-esterified fatty acids (NEFA), β-hydroxybutyrate (BHB), insulin, glucose, Ca, Cl, Mg, P, K, Na, aspartate transaminase (AST), alanine transaminase (ALT) and urea were evaluated. Signifi cant decrease in the levels of T3, T4 and TSH was found in the postpartum period. The values of T3 and T4 were negatively correlated with NEFA and BHB levels, and TSH values were negatively correlated with NEFA. A critical T3 threshold was found by means of ROC analysis for predicting the risk of ketosis. T3 values < 1.23 nmol/L were associated with BHB > 1.10 mmol/L in postpartum, which represents the BHB threshold commonly used as the indicator of hyperketonaemia. The results confirm that the peripartum period is accompanied by marked changes in circulating thyroid hormone profile that is correlated with lipomobilization predictors.Fiore EnricoGiambelluca SoniaMorgante MassimoPiccione GiuseppeVazzana IreneContiero BarbaraOrefice TizianaArfuso FrancescaGianesella MatteoSciendoarticledairy cowmetabolismthyroid hormonetransition periodVeterinary medicineSF600-1100ENActa Veterinaria, Vol 67, Iss 3, Pp 318-330 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	dairy cow metabolism thyroid hormone transition period Veterinary medicine SF600-1100
spellingShingle	dairy cow metabolism thyroid hormone transition period Veterinary medicine SF600-1100 Fiore Enrico Giambelluca Sonia Morgante Massimo Piccione Giuseppe Vazzana Irene Contiero Barbara Orefice Tiziana Arfuso Francesca Gianesella Matteo Changes in Thyroid Hormones Levels and Metabolism in Dairy Cows around Calving
description	The hormonal activity of the thyroid gland has an important role in ruminants for the modulation of metabolic variables. In this study changes in thyroid hormones and biochemical parameters in dairy cows around calving were evaluated and the critical thyroid hormones thresholds for predicting the risk of ketosis were estimated. Blood samples were collected from 82 dairy cows at 5±3 days pre-partum and 5±3 days postpartum. Serum values of triiodothyronine (T3), thyroxine (T4), thyroid-stimulating hormone (TSH), non-esterified fatty acids (NEFA), β-hydroxybutyrate (BHB), insulin, glucose, Ca, Cl, Mg, P, K, Na, aspartate transaminase (AST), alanine transaminase (ALT) and urea were evaluated. Signifi cant decrease in the levels of T3, T4 and TSH was found in the postpartum period. The values of T3 and T4 were negatively correlated with NEFA and BHB levels, and TSH values were negatively correlated with NEFA. A critical T3 threshold was found by means of ROC analysis for predicting the risk of ketosis. T3 values < 1.23 nmol/L were associated with BHB > 1.10 mmol/L in postpartum, which represents the BHB threshold commonly used as the indicator of hyperketonaemia. The results confirm that the peripartum period is accompanied by marked changes in circulating thyroid hormone profile that is correlated with lipomobilization predictors.
format	article
author	Fiore Enrico Giambelluca Sonia Morgante Massimo Piccione Giuseppe Vazzana Irene Contiero Barbara Orefice Tiziana Arfuso Francesca Gianesella Matteo
author_facet	Fiore Enrico Giambelluca Sonia Morgante Massimo Piccione Giuseppe Vazzana Irene Contiero Barbara Orefice Tiziana Arfuso Francesca Gianesella Matteo
author_sort	Fiore Enrico
title	Changes in Thyroid Hormones Levels and Metabolism in Dairy Cows around Calving
title_short	Changes in Thyroid Hormones Levels and Metabolism in Dairy Cows around Calving
title_full	Changes in Thyroid Hormones Levels and Metabolism in Dairy Cows around Calving
title_fullStr	Changes in Thyroid Hormones Levels and Metabolism in Dairy Cows around Calving
title_full_unstemmed	Changes in Thyroid Hormones Levels and Metabolism in Dairy Cows around Calving
title_sort	changes in thyroid hormones levels and metabolism in dairy cows around calving
publisher	Sciendo
publishDate	2017
url	https://doaj.org/article/15331a90f9024462ae4ad1635cb92ea5
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Changes in Thyroid Hormones Levels and Metabolism in Dairy Cows around Calving

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