Development of a Model System for Tick-Borne Flavivirus Persistence in HEK 293T Cells

ABSTRACT We devised a model system to study persistent infection by the tick-borne flavivirus Langat virus (LGTV) in 293T cells. Infection with a molecularly cloned LGTV strain produced an acute lytic crisis that left few surviving cells. The culture was repopulated by cells that were ~90% positive...

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Autores principales: Luwanika Mlera, Danielle K. Offerdahl, Craig Martens, Stephen F. Porcella, Wessam Melik, Marshall E. Bloom
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2015
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Acceso en línea:https://doaj.org/article/153475668fb544a18940f4a7d55a880d
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