Hysteresis control of epithelial-mesenchymal transition dynamics conveys a distinct program with enhanced metastatic ability
The epithelial-mesenchymal transition (EMT) is a dynamic process that plays important roles in cancer progression and metastasis. Here, the authors characterize a non-linear hysteretic response of E-cadherin repression during TGFβ-induced EMT that is controlled by the strength of the miR-200s/ZEBs n...
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Autores principales: | Toni Celià-Terrassa, Caleb Bastian, Daniel D. Liu, Brian Ell, Nicole M. Aiello, Yong Wei, Jose Zamalloa, Andres M. Blanco, Xiang Hang, Dmitriy Kunisky, Wenyang Li, Elizabeth D. Williams, Herschel Rabitz, Yibin Kang |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/15369d2c47794345b6112dc4b6b051de |
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