Synapse loss and progress of Alzheimer’s disease -A network model
Abstract We present observational evidence from studies on primary cortical cultures from AD transgenic mice, APPSwe/PS1ΔE9 (APP/PS1) mice, for significant decrease in total spine density at DIV-15 and onward. This indicates reduction in potential healthy synapses and strength of connections among n...
Guardado en:
Autores principales: | G. Kashyap, D. Bapat, D. Das, R. Gowaikar, R. E. Amritkar, G. Rangarajan, V. Ravindranath, G. Ambika |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/1536a4a95e344c3ba52a07cabdc745fe |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer’s disease patient iPSC-derived cerebral organoids
por: Jing Zhao, et al.
Publicado: (2020) -
Author Correction: APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer’s disease patient iPSC-derived cerebral organoids
por: Jing Zhao, et al.
Publicado: (2021) -
Impairments of spatial memory in an Alzheimer’s disease model via degeneration of hippocampal cholinergic synapses
por: Houze Zhu, et al.
Publicado: (2017) -
Disease progression modeling of Alzheimer’s disease according to education level
por: Ko Woon Kim, et al.
Publicado: (2020) -
Gaussian synapses for probabilistic neural networks
por: Amritanand Sebastian, et al.
Publicado: (2019)