Structures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism

The genome of double-stranded DNA bacteriophages is delivered to host cells through the viral portal and tail structures. Here the authors describe structures of the bacteriophage T7 portal and the 1.5 MDa tail complex formed by the portal protein, adaptor protein and nozzle, providing insight into...

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Autores principales: Ana Cuervo, Montserrat Fàbrega-Ferrer, Cristina Machón, José Javier Conesa, Francisco J. Fernández, Rosa Pérez-Luque, Mar Pérez-Ruiz, Joan Pous, M. Cristina Vega, José L. Carrascosa, Miquel Coll
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/1537915043a149bc8b55f855d29da349
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spelling oai:doaj.org-article:1537915043a149bc8b55f855d29da3492021-12-02T17:01:55ZStructures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism10.1038/s41467-019-11705-92041-1723https://doaj.org/article/1537915043a149bc8b55f855d29da3492019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11705-9https://doaj.org/toc/2041-1723The genome of double-stranded DNA bacteriophages is delivered to host cells through the viral portal and tail structures. Here the authors describe structures of the bacteriophage T7 portal and the 1.5 MDa tail complex formed by the portal protein, adaptor protein and nozzle, providing insight into how the portal and tail machinery work during DNA packaging and ejection.Ana CuervoMontserrat Fàbrega-FerrerCristina MachónJosé Javier ConesaFrancisco J. FernándezRosa Pérez-LuqueMar Pérez-RuizJoan PousM. Cristina VegaJosé L. CarrascosaMiquel CollNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ana Cuervo
Montserrat Fàbrega-Ferrer
Cristina Machón
José Javier Conesa
Francisco J. Fernández
Rosa Pérez-Luque
Mar Pérez-Ruiz
Joan Pous
M. Cristina Vega
José L. Carrascosa
Miquel Coll
Structures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism
description The genome of double-stranded DNA bacteriophages is delivered to host cells through the viral portal and tail structures. Here the authors describe structures of the bacteriophage T7 portal and the 1.5 MDa tail complex formed by the portal protein, adaptor protein and nozzle, providing insight into how the portal and tail machinery work during DNA packaging and ejection.
format article
author Ana Cuervo
Montserrat Fàbrega-Ferrer
Cristina Machón
José Javier Conesa
Francisco J. Fernández
Rosa Pérez-Luque
Mar Pérez-Ruiz
Joan Pous
M. Cristina Vega
José L. Carrascosa
Miquel Coll
author_facet Ana Cuervo
Montserrat Fàbrega-Ferrer
Cristina Machón
José Javier Conesa
Francisco J. Fernández
Rosa Pérez-Luque
Mar Pérez-Ruiz
Joan Pous
M. Cristina Vega
José L. Carrascosa
Miquel Coll
author_sort Ana Cuervo
title Structures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism
title_short Structures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism
title_full Structures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism
title_fullStr Structures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism
title_full_unstemmed Structures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism
title_sort structures of t7 bacteriophage portal and tail suggest a viral dna retention and ejection mechanism
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/1537915043a149bc8b55f855d29da349
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