Deletion of Trim28 in committed adipocytes promotes obesity but preserves glucose tolerance

Deletion of Trim28 in committed adipocytes promotes obesity but preserves glucose tolerance

The genetic determinants of sex-specific differences in obesity are still incompletely understood. Here, the authors demonstrate that adipocyte specific loss of Trim28 in committed adipocytes leads to sex specific differences in the development of obesity, and that this phenotype is associated with...

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Bibliographic Details
Main Authors: Simon T. Bond, Emily J. King, Darren C. Henstridge, Adrian Tran, Sarah C. Moody, Christine Yang, Yingying Liu, Natalie A. Mellett, Artika P. Nath, Michael Inouye, Elizabeth J. Tarling, Thomas Q. de Aguiar Vallim, Peter J. Meikle, Anna C. Calkin, Brian G. Drew
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Science
Q
Online Access:https://doaj.org/article/153ba01f3e9e4f4784fc02d6c030c7c9
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