RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail

RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail

RNA m6A methylation is known to be dysregulated in many cancers. Here, the authors show that m6A methylation of Snail mRNA regulates its translation with potential effects on epithelial mesenchymal transition.

Guardado en:
Detalles Bibliográficos
Autores principales: Xinyao Lin, Guoshi Chai, Yingmin Wu, Jiexin Li, Feng Chen, Jianzhao Liu, Guanzheng Luo, Jordi Tauler, Jun Du, Shuibin Lin, Chuan He, Hongsheng Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/15400780c3c04521ab71d2f2193c0bae
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:15400780c3c04521ab71d2f2193c0bae
record_format dspace
spelling oai:doaj.org-article:15400780c3c04521ab71d2f2193c0bae2021-12-02T16:58:14ZRNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail10.1038/s41467-019-09865-92041-1723https://doaj.org/article/15400780c3c04521ab71d2f2193c0bae2019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09865-9https://doaj.org/toc/2041-1723RNA m6A methylation is known to be dysregulated in many cancers. Here, the authors show that m6A methylation of Snail mRNA regulates its translation with potential effects on epithelial mesenchymal transition.Xinyao LinGuoshi ChaiYingmin WuJiexin LiFeng ChenJianzhao LiuGuanzheng LuoJordi TaulerJun DuShuibin LinChuan HeHongsheng WangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xinyao Lin
Guoshi Chai
Yingmin Wu
Jiexin Li
Feng Chen
Jianzhao Liu
Guanzheng Luo
Jordi Tauler
Jun Du
Shuibin Lin
Chuan He
Hongsheng Wang
RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail
description RNA m6A methylation is known to be dysregulated in many cancers. Here, the authors show that m6A methylation of Snail mRNA regulates its translation with potential effects on epithelial mesenchymal transition.
format article
author Xinyao Lin
Guoshi Chai
Yingmin Wu
Jiexin Li
Feng Chen
Jianzhao Liu
Guanzheng Luo
Jordi Tauler
Jun Du
Shuibin Lin
Chuan He
Hongsheng Wang
author_facet Xinyao Lin
Guoshi Chai
Yingmin Wu
Jiexin Li
Feng Chen
Jianzhao Liu
Guanzheng Luo
Jordi Tauler
Jun Du
Shuibin Lin
Chuan He
Hongsheng Wang
author_sort Xinyao Lin
title RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail
title_short RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail
title_full RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail
title_fullStr RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail
title_full_unstemmed RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail
title_sort rna m6a methylation regulates the epithelial mesenchymal transition of cancer cells and translation of snail
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/15400780c3c04521ab71d2f2193c0bae
work_keys_str_mv AT xinyaolin rnam6amethylationregulatestheepithelialmesenchymaltransitionofcancercellsandtranslationofsnail
AT guoshichai rnam6amethylationregulatestheepithelialmesenchymaltransitionofcancercellsandtranslationofsnail
AT yingminwu rnam6amethylationregulatestheepithelialmesenchymaltransitionofcancercellsandtranslationofsnail
AT jiexinli rnam6amethylationregulatestheepithelialmesenchymaltransitionofcancercellsandtranslationofsnail
AT fengchen rnam6amethylationregulatestheepithelialmesenchymaltransitionofcancercellsandtranslationofsnail
AT jianzhaoliu rnam6amethylationregulatestheepithelialmesenchymaltransitionofcancercellsandtranslationofsnail
AT guanzhengluo rnam6amethylationregulatestheepithelialmesenchymaltransitionofcancercellsandtranslationofsnail
AT jorditauler rnam6amethylationregulatestheepithelialmesenchymaltransitionofcancercellsandtranslationofsnail
AT jundu rnam6amethylationregulatestheepithelialmesenchymaltransitionofcancercellsandtranslationofsnail
AT shuibinlin rnam6amethylationregulatestheepithelialmesenchymaltransitionofcancercellsandtranslationofsnail
AT chuanhe rnam6amethylationregulatestheepithelialmesenchymaltransitionofcancercellsandtranslationofsnail
AT hongshengwang rnam6amethylationregulatestheepithelialmesenchymaltransitionofcancercellsandtranslationofsnail
_version_ 1718382372733321216

Ejemplares similares