Blocking IL-17A enhances tumor response to anti-PD-1 immunotherapy in microsatellite stable colorectal cancer

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Blocking IL-17A enhances tumor response to anti-PD-1 immunotherapy in microsatellite stable colorectal cancer

Background Immune checkpoint inhibitors (ICIs), including anti-PD-1 therapy, have limited efficacy in patients with microsatellite stable (MSS) colorectal cancer (CRC). Interleukin 17A (IL-17A) activity leads to a protumor microenvironment, dependent on its ability to induce the production of inflam...

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Auteurs principaux:	Chao Liu, Yang Yao, Jiaqi Shi, Ruiqi Liu, Bojun Wang, Jie Lian, Haoxiu Sun, Chunhui Zhang, Lin Fang, Xin Guan, Shuling Han, Fei Zhan, Shengnan Luo, Yuanfei Yao, Tongsen Zheng, Yanqiao Zhang
Format:	article
Langue:	EN
Publié:	BMJ Publishing Group 2021
Sujets:	Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Accès en ligne:	https://doaj.org/article/1543fccbb7ab42599845ba4d1df732b1
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

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