Aspergillus Secondary Metabolite Database, a resource to understand the Secondary metabolome of Aspergillus genus

Abstract Aspergillus is a genus of ubiquitous fungi that are pathologically & therapeutically important. Aspergillus Secondary Metabolites Database (A2MDB) is a curated compendium of information on Aspergillus & its secondary metabolome. A2MDB catalogs 807 unique non-redundantsecondary metab...

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Autores principales:	Varahalarao Vadlapudi, Nabajyoti Borah, Kanaka Raju Yellusani, Sriramya Gade, Prabhakar Reddy, Maheshwari Rajamanikyam, Lakshmi Narasimha Santosh Vempati, Satya Prakash Gubbala, Pankaj Chopra, Suryanarayana Murty Upadhyayula, Ramars Amanchy
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/154447ed149e4a3ab5dcab4ce848faf8
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spelling	oai:doaj.org-article:154447ed149e4a3ab5dcab4ce848faf82021-12-02T16:08:22ZAspergillus Secondary Metabolite Database, a resource to understand the Secondary metabolome of Aspergillus genus10.1038/s41598-017-07436-w2045-2322https://doaj.org/article/154447ed149e4a3ab5dcab4ce848faf82017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-07436-whttps://doaj.org/toc/2045-2322Abstract Aspergillus is a genus of ubiquitous fungi that are pathologically & therapeutically important. Aspergillus Secondary Metabolites Database (A2MDB) is a curated compendium of information on Aspergillus & its secondary metabolome. A2MDB catalogs 807 unique non-redundantsecondary metabolites derived from 675 Aspergillus species. A2MDB has a compilation of 100 cellular targets of secondary metabolites, 44 secondary metabolic pathways, 150 electron and light microscopy images of various Aspergillus species. A phylogenetic representation of over 2500 strains has been provided. A2MDB presents a detailed chemical information of secondary metabolites and their mycotoxins. Molecular docking models of metabolite-target protein interactions have been put together. A2MDB also has epidemiological data representing Aspergillosis and global occurrence of Aspergillus species. Furthermore a novel classification of Aspergillosis along with 370 case reports with images, were made available. For each metabolite catalogued, external links to related databases have been provided. All this data is available on A2MDB, launched through Indian Institute of Chemical Technology, Hyderabad, India, as an open resource http://www.iictindia.org/A2MDB . We believe A2MDB is of practical relevance to the scientific community that is in pursuit of novel therapeutics.Varahalarao VadlapudiNabajyoti BorahKanaka Raju YellusaniSriramya GadePrabhakar ReddyMaheshwari RajamanikyamLakshmi Narasimha Santosh VempatiSatya Prakash GubbalaPankaj ChopraSuryanarayana Murty UpadhyayulaRamars AmanchyNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Varahalarao Vadlapudi Nabajyoti Borah Kanaka Raju Yellusani Sriramya Gade Prabhakar Reddy Maheshwari Rajamanikyam Lakshmi Narasimha Santosh Vempati Satya Prakash Gubbala Pankaj Chopra Suryanarayana Murty Upadhyayula Ramars Amanchy Aspergillus Secondary Metabolite Database, a resource to understand the Secondary metabolome of Aspergillus genus
description	Abstract Aspergillus is a genus of ubiquitous fungi that are pathologically & therapeutically important. Aspergillus Secondary Metabolites Database (A2MDB) is a curated compendium of information on Aspergillus & its secondary metabolome. A2MDB catalogs 807 unique non-redundantsecondary metabolites derived from 675 Aspergillus species. A2MDB has a compilation of 100 cellular targets of secondary metabolites, 44 secondary metabolic pathways, 150 electron and light microscopy images of various Aspergillus species. A phylogenetic representation of over 2500 strains has been provided. A2MDB presents a detailed chemical information of secondary metabolites and their mycotoxins. Molecular docking models of metabolite-target protein interactions have been put together. A2MDB also has epidemiological data representing Aspergillosis and global occurrence of Aspergillus species. Furthermore a novel classification of Aspergillosis along with 370 case reports with images, were made available. For each metabolite catalogued, external links to related databases have been provided. All this data is available on A2MDB, launched through Indian Institute of Chemical Technology, Hyderabad, India, as an open resource http://www.iictindia.org/A2MDB . We believe A2MDB is of practical relevance to the scientific community that is in pursuit of novel therapeutics.
format	article
author	Varahalarao Vadlapudi Nabajyoti Borah Kanaka Raju Yellusani Sriramya Gade Prabhakar Reddy Maheshwari Rajamanikyam Lakshmi Narasimha Santosh Vempati Satya Prakash Gubbala Pankaj Chopra Suryanarayana Murty Upadhyayula Ramars Amanchy
author_facet	Varahalarao Vadlapudi Nabajyoti Borah Kanaka Raju Yellusani Sriramya Gade Prabhakar Reddy Maheshwari Rajamanikyam Lakshmi Narasimha Santosh Vempati Satya Prakash Gubbala Pankaj Chopra Suryanarayana Murty Upadhyayula Ramars Amanchy
author_sort	Varahalarao Vadlapudi
title	Aspergillus Secondary Metabolite Database, a resource to understand the Secondary metabolome of Aspergillus genus
title_short	Aspergillus Secondary Metabolite Database, a resource to understand the Secondary metabolome of Aspergillus genus
title_full	Aspergillus Secondary Metabolite Database, a resource to understand the Secondary metabolome of Aspergillus genus
title_fullStr	Aspergillus Secondary Metabolite Database, a resource to understand the Secondary metabolome of Aspergillus genus
title_full_unstemmed	Aspergillus Secondary Metabolite Database, a resource to understand the Secondary metabolome of Aspergillus genus
title_sort	aspergillus secondary metabolite database, a resource to understand the secondary metabolome of aspergillus genus
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/154447ed149e4a3ab5dcab4ce848faf8
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Aspergillus Secondary Metabolite Database, a resource to understand the Secondary metabolome of Aspergillus genus

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