Development of graphene oxide-wrapped gold nanorods as robust nanoplatform for ultrafast near-infrared SERS bioimaging

Xuejun Qiu,1 Xinru You,2 Xing Chen,2 Haolin Chen,1 Arvind Dhinakar,3 Songhao Liu,1 Zhouyi Guo,1 Jun Wu,2,4 Zhiming Liu1 1SATCM Third Grade Laboratory of Chinese Medicine and Photonics Technology, College of Biophotonics, South China Normal University, 2Guangdong Provincial Key Laboratory of Sensor...

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Autores principales:	Qiu XJ, You XR, Chen X, Chen HL, Dhinakar A, Liu SH, Guo ZY, Wu J, Liu ZM
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	Gold nanorods graphene oxide near-infrared bioimaging surface-enhanced Raman scattering Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/154a59078fcf42ec9b207c99460ca119
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spelling	oai:doaj.org-article:154a59078fcf42ec9b207c99460ca1192021-12-02T08:20:26ZDevelopment of graphene oxide-wrapped gold nanorods as robust nanoplatform for ultrafast near-infrared SERS bioimaging1178-2013https://doaj.org/article/154a59078fcf42ec9b207c99460ca1192017-06-01T00:00:00Zhttps://www.dovepress.com/development-of-graphene-oxide-wrapped-gold-nanorods-as-robust-nanoplat-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Xuejun Qiu,1 Xinru You,2 Xing Chen,2 Haolin Chen,1 Arvind Dhinakar,3 Songhao Liu,1 Zhouyi Guo,1 Jun Wu,2,4 Zhiming Liu1 1SATCM Third Grade Laboratory of Chinese Medicine and Photonics Technology, College of Biophotonics, South China Normal University, 2Guangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, School of Engineering, Sun Yat-Sen University, Guangzhou, Guangdong, People’s Republic of China; 3Faculty of Engineering, University of Waterloo, Waterloo, ON, Canada; 4Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education, Sun Yat-Sen University, Guangzhou, Guangdong, People’s Republic of China Abstract: The rapid development of near-infrared surface-enhanced Raman scattering (NIR SERS) imaging technology has attracted strong interest from scientists and clinicians due to its narrow spectral bandwidth, low background interference, and deep imaging depth. In this report, the graphene oxide (GO)-wrapped gold nanorods (GO@GNRs) were developed as a smart and robust nanoplatform for ultrafast NIR SERS bioimaging. The fabricated GO@GNRs could efficiently load various NIR probes, and the in vitro evaluation indicated that the nanoplatform could exhibit a higher NIR SERS activity in comparison with traditional gold nanostructures. The GOs were prepared by directly pyrolyzing citric acid for greater convenience, and GO@GNRs were fabricated via a facile synthesis strategy. Higher NIR SERS activity, facile synthesis method, excellent biocompatibility, and superb stability make the GO@GNRs/probe complex promising nanoprobes for NIR SERS-based bioimaging applications. Keywords: gold nanorods, graphene oxide, near-infrared bioimaging, surface-enhanced Raman scatteringQiu XJYou XRChen XChen HLDhinakar ALiu SHGuo ZYWu JLiu ZMDove Medical PressarticleGold nanorodsgraphene oxidenear-infrared bioimagingsurface-enhanced Raman scatteringMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 12, Pp 4349-4360 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Gold nanorods graphene oxide near-infrared bioimaging surface-enhanced Raman scattering Medicine (General) R5-920
spellingShingle	Gold nanorods graphene oxide near-infrared bioimaging surface-enhanced Raman scattering Medicine (General) R5-920 Qiu XJ You XR Chen X Chen HL Dhinakar A Liu SH Guo ZY Wu J Liu ZM Development of graphene oxide-wrapped gold nanorods as robust nanoplatform for ultrafast near-infrared SERS bioimaging
description	Xuejun Qiu,1 Xinru You,2 Xing Chen,2 Haolin Chen,1 Arvind Dhinakar,3 Songhao Liu,1 Zhouyi Guo,1 Jun Wu,2,4 Zhiming Liu1 1SATCM Third Grade Laboratory of Chinese Medicine and Photonics Technology, College of Biophotonics, South China Normal University, 2Guangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, School of Engineering, Sun Yat-Sen University, Guangzhou, Guangdong, People’s Republic of China; 3Faculty of Engineering, University of Waterloo, Waterloo, ON, Canada; 4Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education, Sun Yat-Sen University, Guangzhou, Guangdong, People’s Republic of China Abstract: The rapid development of near-infrared surface-enhanced Raman scattering (NIR SERS) imaging technology has attracted strong interest from scientists and clinicians due to its narrow spectral bandwidth, low background interference, and deep imaging depth. In this report, the graphene oxide (GO)-wrapped gold nanorods (GO@GNRs) were developed as a smart and robust nanoplatform for ultrafast NIR SERS bioimaging. The fabricated GO@GNRs could efficiently load various NIR probes, and the in vitro evaluation indicated that the nanoplatform could exhibit a higher NIR SERS activity in comparison with traditional gold nanostructures. The GOs were prepared by directly pyrolyzing citric acid for greater convenience, and GO@GNRs were fabricated via a facile synthesis strategy. Higher NIR SERS activity, facile synthesis method, excellent biocompatibility, and superb stability make the GO@GNRs/probe complex promising nanoprobes for NIR SERS-based bioimaging applications. Keywords: gold nanorods, graphene oxide, near-infrared bioimaging, surface-enhanced Raman scattering
format	article
author	Qiu XJ You XR Chen X Chen HL Dhinakar A Liu SH Guo ZY Wu J Liu ZM
author_facet	Qiu XJ You XR Chen X Chen HL Dhinakar A Liu SH Guo ZY Wu J Liu ZM
author_sort	Qiu XJ
title	Development of graphene oxide-wrapped gold nanorods as robust nanoplatform for ultrafast near-infrared SERS bioimaging
title_short	Development of graphene oxide-wrapped gold nanorods as robust nanoplatform for ultrafast near-infrared SERS bioimaging
title_full	Development of graphene oxide-wrapped gold nanorods as robust nanoplatform for ultrafast near-infrared SERS bioimaging
title_fullStr	Development of graphene oxide-wrapped gold nanorods as robust nanoplatform for ultrafast near-infrared SERS bioimaging
title_full_unstemmed	Development of graphene oxide-wrapped gold nanorods as robust nanoplatform for ultrafast near-infrared SERS bioimaging
title_sort	development of graphene oxide-wrapped gold nanorods as robust nanoplatform for ultrafast near-infrared sers bioimaging
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/154a59078fcf42ec9b207c99460ca119
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Development of graphene oxide-wrapped gold nanorods as robust nanoplatform for ultrafast near-infrared SERS bioimaging

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