Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain

Public antibody clonotypes that recognize SARS-CoV-2 spike protein are important for protection against COVID-19. Here, the authors characterize sequence motifs in the heavy chain complementarity-determining region (CDR) H3s of two public clonotypes and their association with light chain identity.

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Autores principales:	Timothy J. C. Tan, Meng Yuan, Kaylee Kuzelka, Gilberto C. Padron, Jacob R. Beal, Xin Chen, Yiquan Wang, Joel Rivera-Cardona, Xueyong Zhu, Beth M. Stadtmueller, Christopher B. Brooke, Ian A. Wilson, Nicholas C. Wu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/157170aa8b7740109a5737bf82c1118d
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spelling	oai:doaj.org-article:157170aa8b7740109a5737bf82c1118d2021-12-02T16:06:03ZSequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain10.1038/s41467-021-24123-72041-1723https://doaj.org/article/157170aa8b7740109a5737bf82c1118d2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24123-7https://doaj.org/toc/2041-1723Public antibody clonotypes that recognize SARS-CoV-2 spike protein are important for protection against COVID-19. Here, the authors characterize sequence motifs in the heavy chain complementarity-determining region (CDR) H3s of two public clonotypes and their association with light chain identity.Timothy J. C. TanMeng YuanKaylee KuzelkaGilberto C. PadronJacob R. BealXin ChenYiquan WangJoel Rivera-CardonaXueyong ZhuBeth M. StadtmuellerChristopher B. BrookeIan A. WilsonNicholas C. WuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Timothy J. C. Tan Meng Yuan Kaylee Kuzelka Gilberto C. Padron Jacob R. Beal Xin Chen Yiquan Wang Joel Rivera-Cardona Xueyong Zhu Beth M. Stadtmueller Christopher B. Brooke Ian A. Wilson Nicholas C. Wu Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain
description	Public antibody clonotypes that recognize SARS-CoV-2 spike protein are important for protection against COVID-19. Here, the authors characterize sequence motifs in the heavy chain complementarity-determining region (CDR) H3s of two public clonotypes and their association with light chain identity.
format	article
author	Timothy J. C. Tan Meng Yuan Kaylee Kuzelka Gilberto C. Padron Jacob R. Beal Xin Chen Yiquan Wang Joel Rivera-Cardona Xueyong Zhu Beth M. Stadtmueller Christopher B. Brooke Ian A. Wilson Nicholas C. Wu
author_facet	Timothy J. C. Tan Meng Yuan Kaylee Kuzelka Gilberto C. Padron Jacob R. Beal Xin Chen Yiquan Wang Joel Rivera-Cardona Xueyong Zhu Beth M. Stadtmueller Christopher B. Brooke Ian A. Wilson Nicholas C. Wu
author_sort	Timothy J. C. Tan
title	Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain
title_short	Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain
title_full	Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain
title_fullStr	Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain
title_full_unstemmed	Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain
title_sort	sequence signatures of two public antibody clonotypes that bind sars-cov-2 receptor binding domain
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/157170aa8b7740109a5737bf82c1118d
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Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain

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