Progression of oral squamous cell carcinoma accompanied with reduced E-cadherin expression but not cadherin switch.

The cadherin switch from E-cadherin to N-cadherin is considered as a hallmark of the epithelial-mesenchymal transition and progression of carcinomas. Although it enhances aggressive behaviors of adenocarcinoma cells, the significance and role of cadherin switch in squamous cell carcinomas (SCCs) are...

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Autores principales: Takashi Hashimoto, Yuichi Soeno, Genta Maeda, Yuji Taya, Takaaki Aoba, Masanori Nasu, Shuichi Kawashiri, Kazushi Imai
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/157384b87b8c40d69f37bf20d290034d
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