PAN-cancer analysis of S-phase enriched lncRNAs identifies oncogenic drivers and biomarkers

Although we know lncRNAs play a role in cancer, the identification of clinically relevant and functional lncRNAs is lacking. Here, the authors identify 633 prognostic markers, 570 S-phase cancer-associated lncRNAs, and show SCAT7 regulates FGF/FGFR and PI3K/AKT/MAPK pathways via interaction with hnR...

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Autores principales:	Mohamad Moustafa Ali, Vijay Suresh Akhade, Subazini Thankaswamy Kosalai, Santhilal Subhash, Luisa Statello, Matthieu Meryet-Figuiere, Jonas Abrahamsson, Tanmoy Mondal, Chandrasekhar Kanduri
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/157be40b73b2441180be0273025f743a
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spelling	oai:doaj.org-article:157be40b73b2441180be0273025f743a2021-12-02T14:40:43ZPAN-cancer analysis of S-phase enriched lncRNAs identifies oncogenic drivers and biomarkers10.1038/s41467-018-03265-12041-1723https://doaj.org/article/157be40b73b2441180be0273025f743a2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03265-1https://doaj.org/toc/2041-1723Although we know lncRNAs play a role in cancer, the identification of clinically relevant and functional lncRNAs is lacking. Here, the authors identify 633 prognostic markers, 570 S-phase cancer-associated lncRNAs, and show SCAT7 regulates FGF/FGFR and PI3K/AKT/MAPK pathways via interaction with hnRNPK/YBX1 complexes.Mohamad Moustafa AliVijay Suresh AkhadeSubazini Thankaswamy KosalaiSanthilal SubhashLuisa StatelloMatthieu Meryet-FiguiereJonas AbrahamssonTanmoy MondalChandrasekhar KanduriNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-20 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mohamad Moustafa Ali Vijay Suresh Akhade Subazini Thankaswamy Kosalai Santhilal Subhash Luisa Statello Matthieu Meryet-Figuiere Jonas Abrahamsson Tanmoy Mondal Chandrasekhar Kanduri PAN-cancer analysis of S-phase enriched lncRNAs identifies oncogenic drivers and biomarkers
description	Although we know lncRNAs play a role in cancer, the identification of clinically relevant and functional lncRNAs is lacking. Here, the authors identify 633 prognostic markers, 570 S-phase cancer-associated lncRNAs, and show SCAT7 regulates FGF/FGFR and PI3K/AKT/MAPK pathways via interaction with hnRNPK/YBX1 complexes.
format	article
author	Mohamad Moustafa Ali Vijay Suresh Akhade Subazini Thankaswamy Kosalai Santhilal Subhash Luisa Statello Matthieu Meryet-Figuiere Jonas Abrahamsson Tanmoy Mondal Chandrasekhar Kanduri
author_facet	Mohamad Moustafa Ali Vijay Suresh Akhade Subazini Thankaswamy Kosalai Santhilal Subhash Luisa Statello Matthieu Meryet-Figuiere Jonas Abrahamsson Tanmoy Mondal Chandrasekhar Kanduri
author_sort	Mohamad Moustafa Ali
title	PAN-cancer analysis of S-phase enriched lncRNAs identifies oncogenic drivers and biomarkers
title_short	PAN-cancer analysis of S-phase enriched lncRNAs identifies oncogenic drivers and biomarkers
title_full	PAN-cancer analysis of S-phase enriched lncRNAs identifies oncogenic drivers and biomarkers
title_fullStr	PAN-cancer analysis of S-phase enriched lncRNAs identifies oncogenic drivers and biomarkers
title_full_unstemmed	PAN-cancer analysis of S-phase enriched lncRNAs identifies oncogenic drivers and biomarkers
title_sort	pan-cancer analysis of s-phase enriched lncrnas identifies oncogenic drivers and biomarkers
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/157be40b73b2441180be0273025f743a
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PAN-cancer analysis of S-phase enriched lncRNAs identifies oncogenic drivers and biomarkers

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