T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells

Microvilli can participate in adhesion or migration of T cells, but whether they are involved in function regulation is unclear. Here the authors show that T cell microvilli form budding vesicles containing T cell signalling components for deposition onto antigen presenting cells (APC) and modulatio...

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Autores principales:	Hye-Ran Kim, YeVin Mun, Kyung-Sik Lee, Yoo-Jin Park, Jeong-Su Park, Jin-Hwa Park, Bu-Nam Jeon, Chang-Hyun Kim, Youngsoo Jun, Young-Min Hyun, Minsoo Kim, Sang-Myeong Lee, Chul-Seung Park, Sin-Hyeog Im, Chang-Duk Jun
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/157de28a8969474ca1a83eae7fbf2e7b
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spelling	oai:doaj.org-article:157de28a8969474ca1a83eae7fbf2e7b2021-12-02T14:40:04ZT cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells10.1038/s41467-018-06090-82041-1723https://doaj.org/article/157de28a8969474ca1a83eae7fbf2e7b2018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06090-8https://doaj.org/toc/2041-1723Microvilli can participate in adhesion or migration of T cells, but whether they are involved in function regulation is unclear. Here the authors show that T cell microvilli form budding vesicles containing T cell signalling components for deposition onto antigen presenting cells (APC) and modulation of APC functions.Hye-Ran KimYeVin MunKyung-Sik LeeYoo-Jin ParkJeong-Su ParkJin-Hwa ParkBu-Nam JeonChang-Hyun KimYoungsoo JunYoung-Min HyunMinsoo KimSang-Myeong LeeChul-Seung ParkSin-Hyeog ImChang-Duk JunNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hye-Ran Kim YeVin Mun Kyung-Sik Lee Yoo-Jin Park Jeong-Su Park Jin-Hwa Park Bu-Nam Jeon Chang-Hyun Kim Youngsoo Jun Young-Min Hyun Minsoo Kim Sang-Myeong Lee Chul-Seung Park Sin-Hyeog Im Chang-Duk Jun T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells
description	Microvilli can participate in adhesion or migration of T cells, but whether they are involved in function regulation is unclear. Here the authors show that T cell microvilli form budding vesicles containing T cell signalling components for deposition onto antigen presenting cells (APC) and modulation of APC functions.
format	article
author	Hye-Ran Kim YeVin Mun Kyung-Sik Lee Yoo-Jin Park Jeong-Su Park Jin-Hwa Park Bu-Nam Jeon Chang-Hyun Kim Youngsoo Jun Young-Min Hyun Minsoo Kim Sang-Myeong Lee Chul-Seung Park Sin-Hyeog Im Chang-Duk Jun
author_facet	Hye-Ran Kim YeVin Mun Kyung-Sik Lee Yoo-Jin Park Jeong-Su Park Jin-Hwa Park Bu-Nam Jeon Chang-Hyun Kim Youngsoo Jun Young-Min Hyun Minsoo Kim Sang-Myeong Lee Chul-Seung Park Sin-Hyeog Im Chang-Duk Jun
author_sort	Hye-Ran Kim
title	T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells
title_short	T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells
title_full	T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells
title_fullStr	T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells
title_full_unstemmed	T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells
title_sort	t cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/157de28a8969474ca1a83eae7fbf2e7b
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T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells

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