Structural basis of the association of HIV-1 matrix protein with DNA.

Structural basis of the association of HIV-1 matrix protein with DNA.

HIV-1 matrix (MA) is a multifunctional protein that is synthesized as a polyprotein that is cleaved by protease during viral maturation. MA contains a cluster of basic residues whose role is controversial. Proposed functions include membrane anchoring, facilitating viral assembly, and directing nucl...

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Autores principales: Mengli Cai, Ying Huang, Robert Craigie, G Marius Clore
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/158391aa08ec49119ed349722d2af401
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