Contribution of ARLTS1 Cys148Arg (T442C) variant with prostate cancer risk and ARLTS1 function in prostate cancer cells.

Contribution of ARLTS1 Cys148Arg (T442C) variant with prostate cancer risk and ARLTS1 function in prostate cancer cells.

ARLTS1 is a recently characterized tumor suppressor gene at 13q14.3, a region frequently deleted in both sporadic and hereditary prostate cancer (PCa). ARLTS1 variants, especially Cys148Arg (T442C), increase susceptibility to different cancers, including PCa. In this study the role of Cys148Arg subs...

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Autores principales: Sanna Siltanen, Tiina Wahlfors, Martin Schindler, Outi R Saramäki, John Patrick Mpindi, Leena Latonen, Robert L Vessella, Teuvo L J Tammela, Olli Kallioniemi, Tapio Visakorpi, Johanna Schleutker
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/1590925213ea4b3aa63622c9307f2430
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