Prevention and treatment of venous thromboembolism in the elderly patient

Enrico Tincani1, Mark A Crowther2, Fabrizio Turrini1, Domenico Prisco31Unità Operativa di Medicina Interna Cardiovascolare, Nuovo Ospedale Civile di Modena S.Agostino-Estense, Modena, Italy; 2McMaster University, St. Joseph’s Hospital and McMaster University, Hamilton, Canada; 3...

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Autores principales:	Enrico Tincani, Mark A Crowther, Fabrizio Turrini, Domenico Prisco
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2007
Materias:	Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/1592b998ef1a406a881e45e95e170d44
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spelling	oai:doaj.org-article:1592b998ef1a406a881e45e95e170d442021-12-02T02:52:38ZPrevention and treatment of venous thromboembolism in the elderly patient1178-1998https://doaj.org/article/1592b998ef1a406a881e45e95e170d442007-07-01T00:00:00Zhttps://www.dovepress.com/prevention-and-treatment-of-venous-thromboembolism-in-the-elderly-pati-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Enrico Tincani1, Mark A Crowther2, Fabrizio Turrini1, Domenico Prisco31Unità Operativa di Medicina Interna Cardiovascolare, Nuovo Ospedale Civile di Modena S.Agostino-Estense, Modena, Italy; 2McMaster University, St. Joseph’s Hospital and McMaster University, Hamilton, Canada; 3Dipartimento di Area Critica Medico Chirurgica, Universita’ di Firenze, Florence, ItalyAbstract: Venous thromboembolism (VTE) is a common complication among hospitalized patients. Pharmacological thromboprophylaxis has emerged as the cornerstone for VTE prevention. As trials on thromboprophylaxis in medical patients have proven the efficacy of both lowmolecular-weight heparins (LMWHs) and unfractionated heparin (UFH), all acutely medical ill patients should be considered for pharmacological thromboprophylaxis. Unlike in the surgical setting where the risk of associated VTE attributable to surgery is well recognized, and where widespread use of pharmacological thromboprophylaxis and early mobilization has resulted in significant reductions in the risk of VTE, appropriate VTE prophylaxis is under-used in medical patients. Many reasons for this under-use have been identified, including low perceived risk of VTE in medical patients, absence of optimal tools for risk assessment, heterogeneity of patients and their diseases, and fear of bleeding complications. A consistent group among hospitalized medical patients is composed of elderly patients with impaired renal function, a condition potentially associated with bleeding. How these patients should be managed is discussed in this review. Particular attention is devoted to LMWHs and fondaparinux and to measures to improve the safety and the efficacy of their use.Keywords: venous thromboembolism, elderly patient, fondaparinuxEnrico TincaniMark A CrowtherFabrizio TurriniDomenico PriscoDove Medical PressarticleGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 2, Pp 237-246 (2007)
institution	DOAJ
collection	DOAJ
language	EN
topic	Geriatrics RC952-954.6
spellingShingle	Geriatrics RC952-954.6 Enrico Tincani Mark A Crowther Fabrizio Turrini Domenico Prisco Prevention and treatment of venous thromboembolism in the elderly patient
description	Enrico Tincani1, Mark A Crowther2, Fabrizio Turrini1, Domenico Prisco31Unità Operativa di Medicina Interna Cardiovascolare, Nuovo Ospedale Civile di Modena S.Agostino-Estense, Modena, Italy; 2McMaster University, St. Joseph’s Hospital and McMaster University, Hamilton, Canada; 3Dipartimento di Area Critica Medico Chirurgica, Universita’ di Firenze, Florence, ItalyAbstract: Venous thromboembolism (VTE) is a common complication among hospitalized patients. Pharmacological thromboprophylaxis has emerged as the cornerstone for VTE prevention. As trials on thromboprophylaxis in medical patients have proven the efficacy of both lowmolecular-weight heparins (LMWHs) and unfractionated heparin (UFH), all acutely medical ill patients should be considered for pharmacological thromboprophylaxis. Unlike in the surgical setting where the risk of associated VTE attributable to surgery is well recognized, and where widespread use of pharmacological thromboprophylaxis and early mobilization has resulted in significant reductions in the risk of VTE, appropriate VTE prophylaxis is under-used in medical patients. Many reasons for this under-use have been identified, including low perceived risk of VTE in medical patients, absence of optimal tools for risk assessment, heterogeneity of patients and their diseases, and fear of bleeding complications. A consistent group among hospitalized medical patients is composed of elderly patients with impaired renal function, a condition potentially associated with bleeding. How these patients should be managed is discussed in this review. Particular attention is devoted to LMWHs and fondaparinux and to measures to improve the safety and the efficacy of their use.Keywords: venous thromboembolism, elderly patient, fondaparinux
format	article
author	Enrico Tincani Mark A Crowther Fabrizio Turrini Domenico Prisco
author_facet	Enrico Tincani Mark A Crowther Fabrizio Turrini Domenico Prisco
author_sort	Enrico Tincani
title	Prevention and treatment of venous thromboembolism in the elderly patient
title_short	Prevention and treatment of venous thromboembolism in the elderly patient
title_full	Prevention and treatment of venous thromboembolism in the elderly patient
title_fullStr	Prevention and treatment of venous thromboembolism in the elderly patient
title_full_unstemmed	Prevention and treatment of venous thromboembolism in the elderly patient
title_sort	prevention and treatment of venous thromboembolism in the elderly patient
publisher	Dove Medical Press
publishDate	2007
url	https://doaj.org/article/1592b998ef1a406a881e45e95e170d44
work_keys_str_mv	AT enricotincani preventionandtreatmentofvenousthromboembolismintheelderlypatient AT markacrowther preventionandtreatmentofvenousthromboembolismintheelderlypatient AT fabrizioturrini preventionandtreatmentofvenousthromboembolismintheelderlypatient AT domenicoprisco preventionandtreatmentofvenousthromboembolismintheelderlypatient
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Prevention and treatment of venous thromboembolism in the elderly patient

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