Corneal Donation: Current Guidelines and Future Direction

Majid Moshirfar,1– 3 Varshini S Odayar,4 Shannon E McCabe,1,5 Yasmyne C Ronquillo1 1Hoopes Vision Research Center, Draper, UT, 84020, USA; 2John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah School of Medicine, Salt Lake City, UT, 84132, USA; 3Utah Lions Ey...

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Autores principales:	Moshirfar M, Odayar VS, McCabe SE, Ronquillo YC
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	donor cornea eye bank covid-19 Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/1594bcb751694b9e8b1b4c9ea152a193
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spelling	oai:doaj.org-article:1594bcb751694b9e8b1b4c9ea152a1932021-12-02T16:39:55ZCorneal Donation: Current Guidelines and Future Direction1177-5483https://doaj.org/article/1594bcb751694b9e8b1b4c9ea152a1932021-07-01T00:00:00Zhttps://www.dovepress.com/corneal-donation-current-guidelines-and-future-direction-peer-reviewed-fulltext-article-OPTHhttps://doaj.org/toc/1177-5483Majid Moshirfar,1– 3 Varshini S Odayar,4 Shannon E McCabe,1,5 Yasmyne C Ronquillo1 1Hoopes Vision Research Center, Draper, UT, 84020, USA; 2John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah School of Medicine, Salt Lake City, UT, 84132, USA; 3Utah Lions Eye Bank, Murray, UT, 84107, USA; 4Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA; 5Mission Hills Eye Center, Pleasant Hill, CA, 94523, USACorrespondence: Majid MoshirfarHoopes Vision Research Center, 11820 State Street, Draper, UT, 84020, USATel +1 801-568-0200Email Cornea2020@me.comPurpose: This review aims to outline current practices and guidelines of corneal donation and eye banking, describes the implications of COVID-19 and emerging diseases on the corneal donor pool, and discusses future trends to improve and increase the efficiency of the processes involved in corneal donation and eye banking.Summary: Corneal screening, preservation, corneal storage, and prevention of systemic disease transmission from donor to recipient have been crucial in shaping the policies of the FDA and eye banks across the world. Eye banks globally have developed varying guidelines and criteria for evaluating the viability of donor corneas. Variables such as the age of the donor, medical history, and potential disease transmission are important screening parameters. While known infectious diseases may be transmissible through the cornea, emerging infectious diseases that are not well studied may be more transmissible than other infections. In particular, coronavirus has impacted corneal transplantation as SARS-CoV-2 expression has been detected in corneal tissue and conjunctiva. In recent years, partial-thickness corneal transplantations have been introduced. Lamellar grafts and other corneal layers are now utilized for transplantation of the specific areas that are damaged.Keywords: donor cornea, eye bank, COVID-19, cornea transplant, keratoplasty, donor recipientMoshirfar MOdayar VSMcCabe SERonquillo YCDove Medical Pressarticledonor corneaeye bankcovid-19OphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 15, Pp 2963-2973 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	donor cornea eye bank covid-19 Ophthalmology RE1-994
spellingShingle	donor cornea eye bank covid-19 Ophthalmology RE1-994 Moshirfar M Odayar VS McCabe SE Ronquillo YC Corneal Donation: Current Guidelines and Future Direction
description	Majid Moshirfar,1– 3 Varshini S Odayar,4 Shannon E McCabe,1,5 Yasmyne C Ronquillo1 1Hoopes Vision Research Center, Draper, UT, 84020, USA; 2John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah School of Medicine, Salt Lake City, UT, 84132, USA; 3Utah Lions Eye Bank, Murray, UT, 84107, USA; 4Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA; 5Mission Hills Eye Center, Pleasant Hill, CA, 94523, USACorrespondence: Majid MoshirfarHoopes Vision Research Center, 11820 State Street, Draper, UT, 84020, USATel +1 801-568-0200Email Cornea2020@me.comPurpose: This review aims to outline current practices and guidelines of corneal donation and eye banking, describes the implications of COVID-19 and emerging diseases on the corneal donor pool, and discusses future trends to improve and increase the efficiency of the processes involved in corneal donation and eye banking.Summary: Corneal screening, preservation, corneal storage, and prevention of systemic disease transmission from donor to recipient have been crucial in shaping the policies of the FDA and eye banks across the world. Eye banks globally have developed varying guidelines and criteria for evaluating the viability of donor corneas. Variables such as the age of the donor, medical history, and potential disease transmission are important screening parameters. While known infectious diseases may be transmissible through the cornea, emerging infectious diseases that are not well studied may be more transmissible than other infections. In particular, coronavirus has impacted corneal transplantation as SARS-CoV-2 expression has been detected in corneal tissue and conjunctiva. In recent years, partial-thickness corneal transplantations have been introduced. Lamellar grafts and other corneal layers are now utilized for transplantation of the specific areas that are damaged.Keywords: donor cornea, eye bank, COVID-19, cornea transplant, keratoplasty, donor recipient
format	article
author	Moshirfar M Odayar VS McCabe SE Ronquillo YC
author_facet	Moshirfar M Odayar VS McCabe SE Ronquillo YC
author_sort	Moshirfar M
title	Corneal Donation: Current Guidelines and Future Direction
title_short	Corneal Donation: Current Guidelines and Future Direction
title_full	Corneal Donation: Current Guidelines and Future Direction
title_fullStr	Corneal Donation: Current Guidelines and Future Direction
title_full_unstemmed	Corneal Donation: Current Guidelines and Future Direction
title_sort	corneal donation: current guidelines and future direction
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/1594bcb751694b9e8b1b4c9ea152a193
work_keys_str_mv	AT moshirfarm cornealdonationcurrentguidelinesandfuturedirection AT odayarvs cornealdonationcurrentguidelinesandfuturedirection AT mccabese cornealdonationcurrentguidelinesandfuturedirection AT ronquilloyc cornealdonationcurrentguidelinesandfuturedirection
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Corneal Donation: Current Guidelines and Future Direction

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