Enantioselective semireduction of allenes

Reduction of allenes poses several challenges in terms of chemo-, regio- and enantio-selectivity. Here, the authors report a rhodium-Josiphos catalytic system that reduces a variety of aryl allenes to chiral benzylic compounds with excellent selectivity and functional group tolerance.

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Bibliographic Details
Main Authors: Zhiwei Chen, Vy M. Dong
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Q
Online Access:https://doaj.org/article/159931391c4b4282a5960d5fa67ad034
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