A role for Separase in telomere protection

A role for Separase in telomere protection

Drosophila telomeres are elongated by transposition of specialized retroelements rather than telomerase activity. Here, the authors show that Separase is enriched at Drosophila telomeres and loss of Sse, the gene encoding Separase, leads to telomere defects, suggesting a role for Separase in telomer...

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Autores principales: Francesca Cipressa, Patrizia Morciano, Giuseppe Bosso, Linda Mannini, Alessandra Galati, Grazia Daniela Raffa, Stefano Cacchione, Antonio Musio, Giovanni Cenci
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Q
Acceso en línea:https://doaj.org/article/159b4a55712b4647ad9cd791721c9e02
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spelling oai:doaj.org-article:159b4a55712b4647ad9cd791721c9e022021-12-02T17:32:36ZA role for Separase in telomere protection10.1038/ncomms104052041-1723https://doaj.org/article/159b4a55712b4647ad9cd791721c9e022016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10405https://doaj.org/toc/2041-1723Drosophila telomeres are elongated by transposition of specialized retroelements rather than telomerase activity. Here, the authors show that Separase is enriched at Drosophila telomeres and loss of Sse, the gene encoding Separase, leads to telomere defects, suggesting a role for Separase in telomere protection.Francesca CipressaPatrizia MorcianoGiuseppe BossoLinda ManniniAlessandra GalatiGrazia Daniela RaffaStefano CacchioneAntonio MusioGiovanni CenciNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Francesca Cipressa
Patrizia Morciano
Giuseppe Bosso
Linda Mannini
Alessandra Galati
Grazia Daniela Raffa
Stefano Cacchione
Antonio Musio
Giovanni Cenci
A role for Separase in telomere protection
description Drosophila telomeres are elongated by transposition of specialized retroelements rather than telomerase activity. Here, the authors show that Separase is enriched at Drosophila telomeres and loss of Sse, the gene encoding Separase, leads to telomere defects, suggesting a role for Separase in telomere protection.
format article
author Francesca Cipressa
Patrizia Morciano
Giuseppe Bosso
Linda Mannini
Alessandra Galati
Grazia Daniela Raffa
Stefano Cacchione
Antonio Musio
Giovanni Cenci
author_facet Francesca Cipressa
Patrizia Morciano
Giuseppe Bosso
Linda Mannini
Alessandra Galati
Grazia Daniela Raffa
Stefano Cacchione
Antonio Musio
Giovanni Cenci
author_sort Francesca Cipressa
title A role for Separase in telomere protection
title_short A role for Separase in telomere protection
title_full A role for Separase in telomere protection
title_fullStr A role for Separase in telomere protection
title_full_unstemmed A role for Separase in telomere protection
title_sort role for separase in telomere protection
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/159b4a55712b4647ad9cd791721c9e02
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