Identification of interferon-stimulated genes that attenuate Ebola virus infection

Here, Kuroda et al. screen a library of nearly 400 interferon-stimulated genes (ISGs) and identify several ISGs that inhibit Ebola virus entry, viral transcription/replication, or virion formation. The study provides insights into interactions between Ebola and the host cells.

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Autores principales:	Makoto Kuroda, Peter J. Halfmann, Lindsay Hill-Batorski, Makoto Ozawa, Tiago J. S. Lopes, Gabriele Neumann, John W. Schoggins, Charles M. Rice, Yoshihiro Kawaoka
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/15a4bdc76f7d489a88f817318de56695
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spelling	oai:doaj.org-article:15a4bdc76f7d489a88f817318de566952021-12-02T14:58:18ZIdentification of interferon-stimulated genes that attenuate Ebola virus infection10.1038/s41467-020-16768-72041-1723https://doaj.org/article/15a4bdc76f7d489a88f817318de566952020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16768-7https://doaj.org/toc/2041-1723Here, Kuroda et al. screen a library of nearly 400 interferon-stimulated genes (ISGs) and identify several ISGs that inhibit Ebola virus entry, viral transcription/replication, or virion formation. The study provides insights into interactions between Ebola and the host cells.Makoto KurodaPeter J. HalfmannLindsay Hill-BatorskiMakoto OzawaTiago J. S. LopesGabriele NeumannJohn W. SchogginsCharles M. RiceYoshihiro KawaokaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Makoto Kuroda Peter J. Halfmann Lindsay Hill-Batorski Makoto Ozawa Tiago J. S. Lopes Gabriele Neumann John W. Schoggins Charles M. Rice Yoshihiro Kawaoka Identification of interferon-stimulated genes that attenuate Ebola virus infection
description	Here, Kuroda et al. screen a library of nearly 400 interferon-stimulated genes (ISGs) and identify several ISGs that inhibit Ebola virus entry, viral transcription/replication, or virion formation. The study provides insights into interactions between Ebola and the host cells.
format	article
author	Makoto Kuroda Peter J. Halfmann Lindsay Hill-Batorski Makoto Ozawa Tiago J. S. Lopes Gabriele Neumann John W. Schoggins Charles M. Rice Yoshihiro Kawaoka
author_facet	Makoto Kuroda Peter J. Halfmann Lindsay Hill-Batorski Makoto Ozawa Tiago J. S. Lopes Gabriele Neumann John W. Schoggins Charles M. Rice Yoshihiro Kawaoka
author_sort	Makoto Kuroda
title	Identification of interferon-stimulated genes that attenuate Ebola virus infection
title_short	Identification of interferon-stimulated genes that attenuate Ebola virus infection
title_full	Identification of interferon-stimulated genes that attenuate Ebola virus infection
title_fullStr	Identification of interferon-stimulated genes that attenuate Ebola virus infection
title_full_unstemmed	Identification of interferon-stimulated genes that attenuate Ebola virus infection
title_sort	identification of interferon-stimulated genes that attenuate ebola virus infection
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/15a4bdc76f7d489a88f817318de56695
work_keys_str_mv	AT makotokuroda identificationofinterferonstimulatedgenesthatattenuateebolavirusinfection AT peterjhalfmann identificationofinterferonstimulatedgenesthatattenuateebolavirusinfection AT lindsayhillbatorski identificationofinterferonstimulatedgenesthatattenuateebolavirusinfection AT makotoozawa identificationofinterferonstimulatedgenesthatattenuateebolavirusinfection AT tiagojslopes identificationofinterferonstimulatedgenesthatattenuateebolavirusinfection AT gabrieleneumann identificationofinterferonstimulatedgenesthatattenuateebolavirusinfection AT johnwschoggins identificationofinterferonstimulatedgenesthatattenuateebolavirusinfection AT charlesmrice identificationofinterferonstimulatedgenesthatattenuateebolavirusinfection AT yoshihirokawaoka identificationofinterferonstimulatedgenesthatattenuateebolavirusinfection
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Identification of interferon-stimulated genes that attenuate Ebola virus infection

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