CT assessment of the increased density of cerebral vessels in plateau region

Abstract In this study, the relationship between the brain parenchymal density, the cerebral vessel density, the mean corpuscular hemoglobin (MCH) content, the mean corpuscular hemoglobin concentration (MCHC), and the morbidity associated with lacunar infarction of residents living in either the pla...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Haiting Zhou, Tsering Tashi, Deli Zhao, Sonam Tsring, Hongwei Liang, Jinling Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/15b9250aa57d4583ad6a3ddd4c4872cb
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:15b9250aa57d4583ad6a3ddd4c4872cb
record_format	dspace
spelling	oai:doaj.org-article:15b9250aa57d4583ad6a3ddd4c4872cb2021-12-02T13:31:11ZCT assessment of the increased density of cerebral vessels in plateau region10.1038/s41598-021-85448-32045-2322https://doaj.org/article/15b9250aa57d4583ad6a3ddd4c4872cb2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-85448-3https://doaj.org/toc/2045-2322Abstract In this study, the relationship between the brain parenchymal density, the cerebral vessel density, the mean corpuscular hemoglobin (MCH) content, the mean corpuscular hemoglobin concentration (MCHC), and the morbidity associated with lacunar infarction of residents living in either the plains or the plateau regions were analyzed and compared for their potential clinical implications. Clinical data from the brain CT scans of individuals living in either the plain or plateau regions (129 each) were collected. Specifically, the CT values for basal ganglia, the middle cerebral artery, and the superior sagittal sinus, along with the number of patients with lacunar infarction, were collected. In addition, the MCH and MCHC values were measured in blood samples collected within 48 h following the CT scans. For statistical analysis, an independent sample t-test, Pearson's correlation test (permutation test), and Chi-squared test were employed. The inhabitants of the plateau had a significantly higher CT value of basal ganglia, the middle cerebral artery, and superior sagittal sinus and also higher levels of MCH and MCHC in the blood (ps < 0.001) than the inhabitants of the plains region. Further, there was a significant positive correlation between the three aforementioned CT values and the MCH and MCHC findings. However, no significant differences were found in the morbidity of lacunar infarction between these two regions (p > 0.05). The inhabitants in the plateau have a significantly higher brain parenchymal density, higher CT value for cerebral vessels density, and higher blood MCH and MCHC levels in comparison with individuals occupying the plains. Concurrently, the parenchymal density and the CT values are shown to be positively correlated with the MCH and MCHC content in the blood.Haiting ZhouTsering TashiDeli ZhaoSonam TsringHongwei LiangJinling ZhangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Haiting Zhou Tsering Tashi Deli Zhao Sonam Tsring Hongwei Liang Jinling Zhang CT assessment of the increased density of cerebral vessels in plateau region
description	Abstract In this study, the relationship between the brain parenchymal density, the cerebral vessel density, the mean corpuscular hemoglobin (MCH) content, the mean corpuscular hemoglobin concentration (MCHC), and the morbidity associated with lacunar infarction of residents living in either the plains or the plateau regions were analyzed and compared for their potential clinical implications. Clinical data from the brain CT scans of individuals living in either the plain or plateau regions (129 each) were collected. Specifically, the CT values for basal ganglia, the middle cerebral artery, and the superior sagittal sinus, along with the number of patients with lacunar infarction, were collected. In addition, the MCH and MCHC values were measured in blood samples collected within 48 h following the CT scans. For statistical analysis, an independent sample t-test, Pearson's correlation test (permutation test), and Chi-squared test were employed. The inhabitants of the plateau had a significantly higher CT value of basal ganglia, the middle cerebral artery, and superior sagittal sinus and also higher levels of MCH and MCHC in the blood (ps < 0.001) than the inhabitants of the plains region. Further, there was a significant positive correlation between the three aforementioned CT values and the MCH and MCHC findings. However, no significant differences were found in the morbidity of lacunar infarction between these two regions (p > 0.05). The inhabitants in the plateau have a significantly higher brain parenchymal density, higher CT value for cerebral vessels density, and higher blood MCH and MCHC levels in comparison with individuals occupying the plains. Concurrently, the parenchymal density and the CT values are shown to be positively correlated with the MCH and MCHC content in the blood.
format	article
author	Haiting Zhou Tsering Tashi Deli Zhao Sonam Tsring Hongwei Liang Jinling Zhang
author_facet	Haiting Zhou Tsering Tashi Deli Zhao Sonam Tsring Hongwei Liang Jinling Zhang
author_sort	Haiting Zhou
title	CT assessment of the increased density of cerebral vessels in plateau region
title_short	CT assessment of the increased density of cerebral vessels in plateau region
title_full	CT assessment of the increased density of cerebral vessels in plateau region
title_fullStr	CT assessment of the increased density of cerebral vessels in plateau region
title_full_unstemmed	CT assessment of the increased density of cerebral vessels in plateau region
title_sort	ct assessment of the increased density of cerebral vessels in plateau region
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/15b9250aa57d4583ad6a3ddd4c4872cb
work_keys_str_mv	AT haitingzhou ctassessmentoftheincreaseddensityofcerebralvesselsinplateauregion AT tseringtashi ctassessmentoftheincreaseddensityofcerebralvesselsinplateauregion AT delizhao ctassessmentoftheincreaseddensityofcerebralvesselsinplateauregion AT sonamtsring ctassessmentoftheincreaseddensityofcerebralvesselsinplateauregion AT hongweiliang ctassessmentoftheincreaseddensityofcerebralvesselsinplateauregion AT jinlingzhang ctassessmentoftheincreaseddensityofcerebralvesselsinplateauregion
_version_	1718392837755633664

CT assessment of the increased density of cerebral vessels in plateau region

Ejemplares similares