Mucosal immunity to the pathogens and tumors involving system "lectins of probiotics - glycopolymers"

The overview of own works is devoted to the new insights to mucosal innate immunity functioning. We described multifunctional lectin systems of probiotic bacteria (LSPB) and their complexes which recognize a wide spectrum of selected glycoconjugates. LSPB (separately or in combinations with other an...

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Autores principales:	M. V. Lakhtin, V. M. Lakhtin, S. S. Afanasjev, V. A. Aleshkin
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2015
Materias:	mucosa congenital immunity probiotic lectins lectin system artificial glycolymers mucins microbiocenosis biotope pathogens tumor-like cells Science Q
Acceso en línea:	https://doaj.org/article/15c647adbaa4437ca6f47a0cc26089cf
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spelling	oai:doaj.org-article:15c647adbaa4437ca6f47a0cc26089cf2021-11-23T06:14:32ZMucosal immunity to the pathogens and tumors involving system "lectins of probiotics - glycopolymers"2541-94202587-9596https://doaj.org/article/15c647adbaa4437ca6f47a0cc26089cf2015-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/73https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The overview of own works is devoted to the new insights to mucosal innate immunity functioning. We described multifunctional lectin systems of probiotic bacteria (LSPB) and their complexes which recognize a wide spectrum of selected glycoconjugates. LSPB (separately or in combinations with other antimicrobials and antipathogen factors) are important contributors to biotope distant protection against pathogens. Being metabolomebiotics, LSPB form reversible complexes to natural and artificial glycopolymers of mucin type that allows building on duty dynamic network of directed cascades of replies of mucosal innate immunity. Probiotic molecular-cellular network "LSPB - glycopolymers" serves as an important synergistic system participating in biotope microbiocenosis antipathogen resistance and in Cross-Talking communications with human protective cells and systems to support prolonged healthy status of mucosa. This network influences mucosa pores, affine texture, tropism and redistribution in biotope. Mucosal innate immunity strategies of LSPB and their complexes against microbial and viral pathogens, early tumor-like mucosal cells are proposed. Biological properties of artificial glycopolymers interacted in LS were compared.M. V. LakhtinV. M. LakhtinS. S. AfanasjevV. A. AleshkinScientific Сentre for Family Health and Human Reproduction Problemsarticlemucosacongenital immunityprobiotic lectinslectin systemartificial glycolymersmucinsmicrobiocenosisbiotopepathogenstumor-like cellsScienceQRUActa Biomedica Scientifica, Vol 0, Iss 3, Pp 62-69 (2015)
institution	DOAJ
collection	DOAJ
language	RU
topic	mucosa congenital immunity probiotic lectins lectin system artificial glycolymers mucins microbiocenosis biotope pathogens tumor-like cells Science Q
spellingShingle	mucosa congenital immunity probiotic lectins lectin system artificial glycolymers mucins microbiocenosis biotope pathogens tumor-like cells Science Q M. V. Lakhtin V. M. Lakhtin S. S. Afanasjev V. A. Aleshkin Mucosal immunity to the pathogens and tumors involving system "lectins of probiotics - glycopolymers"
description	The overview of own works is devoted to the new insights to mucosal innate immunity functioning. We described multifunctional lectin systems of probiotic bacteria (LSPB) and their complexes which recognize a wide spectrum of selected glycoconjugates. LSPB (separately or in combinations with other antimicrobials and antipathogen factors) are important contributors to biotope distant protection against pathogens. Being metabolomebiotics, LSPB form reversible complexes to natural and artificial glycopolymers of mucin type that allows building on duty dynamic network of directed cascades of replies of mucosal innate immunity. Probiotic molecular-cellular network "LSPB - glycopolymers" serves as an important synergistic system participating in biotope microbiocenosis antipathogen resistance and in Cross-Talking communications with human protective cells and systems to support prolonged healthy status of mucosa. This network influences mucosa pores, affine texture, tropism and redistribution in biotope. Mucosal innate immunity strategies of LSPB and their complexes against microbial and viral pathogens, early tumor-like mucosal cells are proposed. Biological properties of artificial glycopolymers interacted in LS were compared.
format	article
author	M. V. Lakhtin V. M. Lakhtin S. S. Afanasjev V. A. Aleshkin
author_facet	M. V. Lakhtin V. M. Lakhtin S. S. Afanasjev V. A. Aleshkin
author_sort	M. V. Lakhtin
title	Mucosal immunity to the pathogens and tumors involving system "lectins of probiotics - glycopolymers"
title_short	Mucosal immunity to the pathogens and tumors involving system "lectins of probiotics - glycopolymers"
title_full	Mucosal immunity to the pathogens and tumors involving system "lectins of probiotics - glycopolymers"
title_fullStr	Mucosal immunity to the pathogens and tumors involving system "lectins of probiotics - glycopolymers"
title_full_unstemmed	Mucosal immunity to the pathogens and tumors involving system "lectins of probiotics - glycopolymers"
title_sort	mucosal immunity to the pathogens and tumors involving system "lectins of probiotics - glycopolymers"
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2015
url	https://doaj.org/article/15c647adbaa4437ca6f47a0cc26089cf
work_keys_str_mv	AT mvlakhtin mucosalimmunitytothepathogensandtumorsinvolvingsystemlectinsofprobioticsglycopolymers AT vmlakhtin mucosalimmunitytothepathogensandtumorsinvolvingsystemlectinsofprobioticsglycopolymers AT ssafanasjev mucosalimmunitytothepathogensandtumorsinvolvingsystemlectinsofprobioticsglycopolymers AT vaaleshkin mucosalimmunitytothepathogensandtumorsinvolvingsystemlectinsofprobioticsglycopolymers
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Mucosal immunity to the pathogens and tumors involving system "lectins of probiotics - glycopolymers"

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