The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication

The atypical chemokine receptor 3 (ACKR3) is known to regulate cell migration, but the underlying mechanisms are unclear. Here, the authors show, from an interactome analysis, ACKR3 association with the gap junction protein Connexin 43 in vivo and ACKR3-mediated inhibition of astrocyte gap junctiona...

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Autores principales:	Amos Fumagalli, Joyce Heuninck, Anne Pizzoccaro, Enora Moutin, Joyce Koenen, Martial Séveno, Thierry Durroux, Marie-Pierre Junier, Géraldine Schlecht-Louf, Francoise Bachelerie, Dagmar Schütz, Ralf Stumm, Martine J. Smit, Nathalie C. Guérineau, Séverine Chaumont-Dubel, Philippe Marin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/15da11b062db485fa8b9ce8e0b203220
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spelling	oai:doaj.org-article:15da11b062db485fa8b9ce8e0b2032202021-12-02T18:14:23ZThe atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication10.1038/s41467-020-18634-y2041-1723https://doaj.org/article/15da11b062db485fa8b9ce8e0b2032202020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18634-yhttps://doaj.org/toc/2041-1723The atypical chemokine receptor 3 (ACKR3) is known to regulate cell migration, but the underlying mechanisms are unclear. Here, the authors show, from an interactome analysis, ACKR3 association with the gap junction protein Connexin 43 in vivo and ACKR3-mediated inhibition of astrocyte gap junctional communication.Amos FumagalliJoyce HeuninckAnne PizzoccaroEnora MoutinJoyce KoenenMartial SévenoThierry DurrouxMarie-Pierre JunierGéraldine Schlecht-LoufFrancoise BachelerieDagmar SchützRalf StummMartine J. SmitNathalie C. GuérineauSéverine Chaumont-DubelPhilippe MarinNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Amos Fumagalli Joyce Heuninck Anne Pizzoccaro Enora Moutin Joyce Koenen Martial Séveno Thierry Durroux Marie-Pierre Junier Géraldine Schlecht-Louf Francoise Bachelerie Dagmar Schütz Ralf Stumm Martine J. Smit Nathalie C. Guérineau Séverine Chaumont-Dubel Philippe Marin The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication
description	The atypical chemokine receptor 3 (ACKR3) is known to regulate cell migration, but the underlying mechanisms are unclear. Here, the authors show, from an interactome analysis, ACKR3 association with the gap junction protein Connexin 43 in vivo and ACKR3-mediated inhibition of astrocyte gap junctional communication.
format	article
author	Amos Fumagalli Joyce Heuninck Anne Pizzoccaro Enora Moutin Joyce Koenen Martial Séveno Thierry Durroux Marie-Pierre Junier Géraldine Schlecht-Louf Francoise Bachelerie Dagmar Schütz Ralf Stumm Martine J. Smit Nathalie C. Guérineau Séverine Chaumont-Dubel Philippe Marin
author_facet	Amos Fumagalli Joyce Heuninck Anne Pizzoccaro Enora Moutin Joyce Koenen Martial Séveno Thierry Durroux Marie-Pierre Junier Géraldine Schlecht-Louf Francoise Bachelerie Dagmar Schütz Ralf Stumm Martine J. Smit Nathalie C. Guérineau Séverine Chaumont-Dubel Philippe Marin
author_sort	Amos Fumagalli
title	The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication
title_short	The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication
title_full	The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication
title_fullStr	The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication
title_full_unstemmed	The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication
title_sort	atypical chemokine receptor 3 interacts with connexin 43 inhibiting astrocytic gap junctional intercellular communication
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/15da11b062db485fa8b9ce8e0b203220
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The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication

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