RAT KIDNEY TISSUES: OXIDATIVE MODIFICATION OF PROTEINS UNDER WATER AND SALT LOADS ASSOCIATED WITH HGCL2 NEPHROPATHY

Some changes in the main indexes of the pro-oxidation system of rat’s kidney tissues exposed to water and salt load on background of the nephropathy caused by mercury chloride were investigated. Conditions of the free-radical oxidation of kidney tissues’ proteins under water and salt load alone or c...

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Autor principal:	Alla VELYKA
Formato:	article
Lenguaje:	EN
Publicado:	Stefan cel Mare University of Suceava 2018
Materias:	water and salt load oxidative protein modification kidney mercury chloride TBAreaction products environmental contamination Food processing and manufacture TP368-456
Acceso en línea:	https://doaj.org/article/15db4c00e9ac48578c301105927264a4
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spelling	oai:doaj.org-article:15db4c00e9ac48578c301105927264a42021-12-02T18:18:25ZRAT KIDNEY TISSUES: OXIDATIVE MODIFICATION OF PROTEINS UNDER WATER AND SALT LOADS ASSOCIATED WITH HGCL2 NEPHROPATHY2068-66092559-6381https://doaj.org/article/15db4c00e9ac48578c301105927264a42018-09-01T00:00:00Zhttp://www.fia.usv.ro/fiajournal/index.php/FENS/article/view/594https://doaj.org/toc/2068-6609https://doaj.org/toc/2559-6381Some changes in the main indexes of the pro-oxidation system of rat’s kidney tissues exposed to water and salt load on background of the nephropathy caused by mercury chloride were investigated. Conditions of the free-radical oxidation of kidney tissues’ proteins under water and salt load alone or complicated by the nephropathy have been analyzed. It is found that water and salt load leads to a higher content of the thiobarbiturate reaction products (TBA-RP) in kidney tissues in comparison with the control experiments while the content of the protein oxidative modification products remains unchanged. Thus, water and salt load causes a higher activation level of free radical oxidation of lipids. A histochemical investigation has been performed to evaluate a degree of the oxidative modification of proteins in rat kidney tissues under water and salt load complicated by the mercuric nephropathy and a higher level of the oxidative modification of proteins has been determined by the Red/Blue coefficient in rat kidneys irrespectively of the load type in case of intoxication with mercury chloride.Alla VELYKAStefan cel Mare University of Suceavaarticlewater and salt loadoxidative protein modificationkidneymercury chlorideTBAreaction productsenvironmental contaminationFood processing and manufactureTP368-456ENFood and Environment Safety, Vol 17, Iss 3, Pp 261 - 271 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	water and salt load oxidative protein modification kidney mercury chloride TBAreaction products environmental contamination Food processing and manufacture TP368-456
spellingShingle	water and salt load oxidative protein modification kidney mercury chloride TBAreaction products environmental contamination Food processing and manufacture TP368-456 Alla VELYKA RAT KIDNEY TISSUES: OXIDATIVE MODIFICATION OF PROTEINS UNDER WATER AND SALT LOADS ASSOCIATED WITH HGCL2 NEPHROPATHY
description	Some changes in the main indexes of the pro-oxidation system of rat’s kidney tissues exposed to water and salt load on background of the nephropathy caused by mercury chloride were investigated. Conditions of the free-radical oxidation of kidney tissues’ proteins under water and salt load alone or complicated by the nephropathy have been analyzed. It is found that water and salt load leads to a higher content of the thiobarbiturate reaction products (TBA-RP) in kidney tissues in comparison with the control experiments while the content of the protein oxidative modification products remains unchanged. Thus, water and salt load causes a higher activation level of free radical oxidation of lipids. A histochemical investigation has been performed to evaluate a degree of the oxidative modification of proteins in rat kidney tissues under water and salt load complicated by the mercuric nephropathy and a higher level of the oxidative modification of proteins has been determined by the Red/Blue coefficient in rat kidneys irrespectively of the load type in case of intoxication with mercury chloride.
format	article
author	Alla VELYKA
author_facet	Alla VELYKA
author_sort	Alla VELYKA
title	RAT KIDNEY TISSUES: OXIDATIVE MODIFICATION OF PROTEINS UNDER WATER AND SALT LOADS ASSOCIATED WITH HGCL2 NEPHROPATHY
title_short	RAT KIDNEY TISSUES: OXIDATIVE MODIFICATION OF PROTEINS UNDER WATER AND SALT LOADS ASSOCIATED WITH HGCL2 NEPHROPATHY
title_full	RAT KIDNEY TISSUES: OXIDATIVE MODIFICATION OF PROTEINS UNDER WATER AND SALT LOADS ASSOCIATED WITH HGCL2 NEPHROPATHY
title_fullStr	RAT KIDNEY TISSUES: OXIDATIVE MODIFICATION OF PROTEINS UNDER WATER AND SALT LOADS ASSOCIATED WITH HGCL2 NEPHROPATHY
title_full_unstemmed	RAT KIDNEY TISSUES: OXIDATIVE MODIFICATION OF PROTEINS UNDER WATER AND SALT LOADS ASSOCIATED WITH HGCL2 NEPHROPATHY
title_sort	rat kidney tissues: oxidative modification of proteins under water and salt loads associated with hgcl2 nephropathy
publisher	Stefan cel Mare University of Suceava
publishDate	2018
url	https://doaj.org/article/15db4c00e9ac48578c301105927264a4
work_keys_str_mv	AT allavelyka ratkidneytissuesoxidativemodificationofproteinsunderwaterandsaltloadsassociatedwithhgcl2nephropathy
_version_	1718378258722979840

RAT KIDNEY TISSUES: OXIDATIVE MODIFICATION OF PROTEINS UNDER WATER AND SALT LOADS ASSOCIATED WITH HGCL2 NEPHROPATHY

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