Accelerated disease progression and robust innate host response in aged SIVmac239-infected Chinese rhesus macaques is associated with enhanced immunosenescence

Accelerated disease progression and robust innate host response in aged SIVmac239-infected Chinese rhesus macaques is associated with enhanced immunosenescence

Abstract The elderly population infected with HIV-1 is often characterized by the rapid AIDS progression and poor treatment outcome, possibly because of immunosenescence resulting from both HIV infection and aging. However, this hypothesis remains to be fully tested. Here, we studied 6 young and 12...

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Autores principales: Hong-Yi Zheng, Ming-Xu Zhang, Min Chen, Jin Jiang, Jia-Hao Song, Xiao-Dong Lian, Ren-Rong Tian, Xiao-Liang Zhang, Lin-Tao Zhang, Wei Pang, Gao-Hong Zhang, Yong-Tang Zheng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/15de5e1f859f40b287d4b3ff06d103af
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