Robust detection of translocations in lymphoma FFPE samples using targeted locus capture-based sequencing
Preservation of cancer biopsies by FFPE introduces DNA fragmentation, hindering analysis of rearrangements. Here the authors introduce FFPE Targeted Locus Capture for identification of translocations in preserved samples.
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Nature Portfolio
2021
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oai:doaj.org-article:15e52e7d12f34aa7b62f485085760e592021-12-02T17:47:14ZRobust detection of translocations in lymphoma FFPE samples using targeted locus capture-based sequencing10.1038/s41467-021-23695-82041-1723https://doaj.org/article/15e52e7d12f34aa7b62f485085760e592021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23695-8https://doaj.org/toc/2041-1723Preservation of cancer biopsies by FFPE introduces DNA fragmentation, hindering analysis of rearrangements. Here the authors introduce FFPE Targeted Locus Capture for identification of translocations in preserved samples.Amin AllahyarMark PieterseJoost SwennenhuisG. Tjitske Los-de VriesMehmet YilmazRoos LeguitRuud W. J. MeijersRobert van der GeizeJoost VermaatArjen ClevenTom van WezelArjan DiepstraLéon C. van KempenNathalie J. HijmeringPhylicia StathiMilan SharmaAdrien S. J. MelquiondPaula J. P. de VreeMarjon J. A. M. VerstegenPeter H. L. KrijgerKarima HajoMarieke SimonisAgata RakszewskaMax van MinDaphne de JongBauke YlstraHarma FeitsmaErik SplinterWouter de LaatNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021) |
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DOAJ |
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EN |
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Science Q |
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Science Q Amin Allahyar Mark Pieterse Joost Swennenhuis G. Tjitske Los-de Vries Mehmet Yilmaz Roos Leguit Ruud W. J. Meijers Robert van der Geize Joost Vermaat Arjen Cleven Tom van Wezel Arjan Diepstra Léon C. van Kempen Nathalie J. Hijmering Phylicia Stathi Milan Sharma Adrien S. J. Melquiond Paula J. P. de Vree Marjon J. A. M. Verstegen Peter H. L. Krijger Karima Hajo Marieke Simonis Agata Rakszewska Max van Min Daphne de Jong Bauke Ylstra Harma Feitsma Erik Splinter Wouter de Laat Robust detection of translocations in lymphoma FFPE samples using targeted locus capture-based sequencing |
| description |
Preservation of cancer biopsies by FFPE introduces DNA fragmentation, hindering analysis of rearrangements. Here the authors introduce FFPE Targeted Locus Capture for identification of translocations in preserved samples. |
| format |
article |
| author |
Amin Allahyar Mark Pieterse Joost Swennenhuis G. Tjitske Los-de Vries Mehmet Yilmaz Roos Leguit Ruud W. J. Meijers Robert van der Geize Joost Vermaat Arjen Cleven Tom van Wezel Arjan Diepstra Léon C. van Kempen Nathalie J. Hijmering Phylicia Stathi Milan Sharma Adrien S. J. Melquiond Paula J. P. de Vree Marjon J. A. M. Verstegen Peter H. L. Krijger Karima Hajo Marieke Simonis Agata Rakszewska Max van Min Daphne de Jong Bauke Ylstra Harma Feitsma Erik Splinter Wouter de Laat |
| author_facet |
Amin Allahyar Mark Pieterse Joost Swennenhuis G. Tjitske Los-de Vries Mehmet Yilmaz Roos Leguit Ruud W. J. Meijers Robert van der Geize Joost Vermaat Arjen Cleven Tom van Wezel Arjan Diepstra Léon C. van Kempen Nathalie J. Hijmering Phylicia Stathi Milan Sharma Adrien S. J. Melquiond Paula J. P. de Vree Marjon J. A. M. Verstegen Peter H. L. Krijger Karima Hajo Marieke Simonis Agata Rakszewska Max van Min Daphne de Jong Bauke Ylstra Harma Feitsma Erik Splinter Wouter de Laat |
| author_sort |
Amin Allahyar |
| title |
Robust detection of translocations in lymphoma FFPE samples using targeted locus capture-based sequencing |
| title_short |
Robust detection of translocations in lymphoma FFPE samples using targeted locus capture-based sequencing |
| title_full |
Robust detection of translocations in lymphoma FFPE samples using targeted locus capture-based sequencing |
| title_fullStr |
Robust detection of translocations in lymphoma FFPE samples using targeted locus capture-based sequencing |
| title_full_unstemmed |
Robust detection of translocations in lymphoma FFPE samples using targeted locus capture-based sequencing |
| title_sort |
robust detection of translocations in lymphoma ffpe samples using targeted locus capture-based sequencing |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/15e52e7d12f34aa7b62f485085760e59 |
| work_keys_str_mv |
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1718379451012612096 |