Astrocytes promote a protective immune response to brain Toxoplasma gondii infection via IL-33-ST2 signaling.

It is of great interest to understand how invading pathogens are sensed within the brain, a tissue with unique challenges to mounting an immune response. The eukaryotic parasite Toxoplasma gondii colonizes the brain of its hosts, and initiates robust immune cell recruitment, but little is known abou...

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Auteurs principaux:	Katherine M Still, Samantha J Batista, Carleigh A O'Brien, Oyebola O Oyesola, Simon P Früh, Lauren M Webb, Igor Smirnov, Michael A Kovacs, Maureen N Cowan, Nikolas W Hayes, Jeremy A Thompson, Elia D Tait Wojno, Tajie H Harris
Format:	article
Langue:	EN
Publié:	Public Library of Science (PLoS) 2020
Sujets:	Immunologic diseases. Allergy RC581-607 Biology (General) QH301-705.5
Accès en ligne:	https://doaj.org/article/15e74006523b4a4c8331d34646726ea9
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Astrocytes promote a protective immune response to brain Toxoplasma gondii infection via IL-33-ST2 signaling.

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