A Bacterial Toxin Perturbs Intracellular Amino Acid Balance To Induce Persistence

To overcome various environmental challenges, bacterial cells can enter a physiologically quiescent state, known as dormancy or persistence, which balances growth and viability. In this study, we report a new mechanism by which a toxin-antitoxin system responds to harsh environmental conditions or...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Xiaofeng Zhou, Michael R. Eckart, Lucy Shapiro
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/15fbbddf83894fcabcc6c901c60da3b3
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:15fbbddf83894fcabcc6c901c60da3b3
record_format	dspace
spelling	oai:doaj.org-article:15fbbddf83894fcabcc6c901c60da3b32021-11-03T18:15:38ZA Bacterial Toxin Perturbs Intracellular Amino Acid Balance To Induce Persistence2161-21292150-751110.1128/mBio.03020-20https://doaj.org/article/15fbbddf83894fcabcc6c901c60da3b32021-02-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.03020-20https://doaj.org/toc/2161-2129https://doaj.org/toc/2150-7511 To overcome various environmental challenges, bacterial cells can enter a physiologically quiescent state, known as dormancy or persistence, which balances growth and viability. In this study, we report a new mechanism by which a toxin-antitoxin system responds to harsh environmental conditions or nutrient deprivation by orchestrating a dormant state while preserving viability.Xiaofeng ZhouMichael R. EckartLucy ShapiroAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 1 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Xiaofeng Zhou Michael R. Eckart Lucy Shapiro A Bacterial Toxin Perturbs Intracellular Amino Acid Balance To Induce Persistence
description	To overcome various environmental challenges, bacterial cells can enter a physiologically quiescent state, known as dormancy or persistence, which balances growth and viability. In this study, we report a new mechanism by which a toxin-antitoxin system responds to harsh environmental conditions or nutrient deprivation by orchestrating a dormant state while preserving viability.
format	article
author	Xiaofeng Zhou Michael R. Eckart Lucy Shapiro
author_facet	Xiaofeng Zhou Michael R. Eckart Lucy Shapiro
author_sort	Xiaofeng Zhou
title	A Bacterial Toxin Perturbs Intracellular Amino Acid Balance To Induce Persistence
title_short	A Bacterial Toxin Perturbs Intracellular Amino Acid Balance To Induce Persistence
title_full	A Bacterial Toxin Perturbs Intracellular Amino Acid Balance To Induce Persistence
title_fullStr	A Bacterial Toxin Perturbs Intracellular Amino Acid Balance To Induce Persistence
title_full_unstemmed	A Bacterial Toxin Perturbs Intracellular Amino Acid Balance To Induce Persistence
title_sort	bacterial toxin perturbs intracellular amino acid balance to induce persistence
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/15fbbddf83894fcabcc6c901c60da3b3
work_keys_str_mv	AT xiaofengzhou abacterialtoxinperturbsintracellularaminoacidbalancetoinducepersistence AT michaelreckart abacterialtoxinperturbsintracellularaminoacidbalancetoinducepersistence AT lucyshapiro abacterialtoxinperturbsintracellularaminoacidbalancetoinducepersistence AT xiaofengzhou bacterialtoxinperturbsintracellularaminoacidbalancetoinducepersistence AT michaelreckart bacterialtoxinperturbsintracellularaminoacidbalancetoinducepersistence AT lucyshapiro bacterialtoxinperturbsintracellularaminoacidbalancetoinducepersistence
_version_	1718445441422458880

A Bacterial Toxin Perturbs Intracellular Amino Acid Balance To Induce Persistence

Ejemplares similares