Precipitating factors, outcomes, and recurrence of diabetic ketoacidosis at a university hospital in Damascus

Aims : To study precipitating factors, outcomes, and recurrence of diabetic ketoacidosis (DKA) at a University hospital at Damascus, the capital of Syria. Patients and Methods : Medical records between 2006 and 2012 were reviewed. One hundred and fifteen admissions for 100 patients with DKA were inc...

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Autores principales:	Zaynab Alourfi, Hakam Homsi
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2015
Materias:	diabetic ketoacidosis dka dka precipitating factor dka recurrence dka outcomes Medicine R
Acceso en línea:	https://doaj.org/article/1609218cbded47ba851c6f98a08219e2
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spelling	oai:doaj.org-article:1609218cbded47ba851c6f98a08219e22021-12-02T16:24:54ZPrecipitating factors, outcomes, and recurrence of diabetic ketoacidosis at a university hospital in Damascus2231-07702249-446410.4103/2231-0770.148503https://doaj.org/article/1609218cbded47ba851c6f98a08219e22015-01-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/2231-0770.148503https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464Aims : To study precipitating factors, outcomes, and recurrence of diabetic ketoacidosis (DKA) at a University hospital at Damascus, the capital of Syria. Patients and Methods : Medical records between 2006 and 2012 were reviewed. One hundred and fifteen admissions for 100 patients with DKA were included. All fulfilled the American Diabetic Association DKA diagnostic criteria. Results: Of 115 admissions of DKA, there were 92 single admission and 23 recurrent admissions (eight patients). The order of precipitating factors of recurrent DKA or single admissions were the same with different percentage. The first and second factors were infection (74% and 48%) and treatment problems (17% and 24%), respectively.Complications rate was significantly higher in the intensive care unit (41.6%), compared to the ward admissions (14.2%). Overall in-hospital mortality rate was 11.3%. The severity of medical conditions that provoke DKA with aging, not the metabolic complications of hyperglycemia or ketoacidosis, were behind this high mortality rate. Patients who died were significantly (P = 0.004) older than patients who were discharged alive. Conclusion: Results concerning precipitating factor were similar to the results of many other studies. However, mortality rate was higher which might be explained by the severity of underlying precipitating illness.Zaynab AlourfiHakam HomsiThieme Medical and Scientific Publishers Pvt. Ltd.articlediabetic ketoacidosisdkadka precipitating factordka recurrencedka outcomesMedicineRENAvicenna Journal of Medicine, Vol 05, Iss 01, Pp 11-15 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	diabetic ketoacidosis dka dka precipitating factor dka recurrence dka outcomes Medicine R
spellingShingle	diabetic ketoacidosis dka dka precipitating factor dka recurrence dka outcomes Medicine R Zaynab Alourfi Hakam Homsi Precipitating factors, outcomes, and recurrence of diabetic ketoacidosis at a university hospital in Damascus
description	Aims : To study precipitating factors, outcomes, and recurrence of diabetic ketoacidosis (DKA) at a University hospital at Damascus, the capital of Syria. Patients and Methods : Medical records between 2006 and 2012 were reviewed. One hundred and fifteen admissions for 100 patients with DKA were included. All fulfilled the American Diabetic Association DKA diagnostic criteria. Results: Of 115 admissions of DKA, there were 92 single admission and 23 recurrent admissions (eight patients). The order of precipitating factors of recurrent DKA or single admissions were the same with different percentage. The first and second factors were infection (74% and 48%) and treatment problems (17% and 24%), respectively.Complications rate was significantly higher in the intensive care unit (41.6%), compared to the ward admissions (14.2%). Overall in-hospital mortality rate was 11.3%. The severity of medical conditions that provoke DKA with aging, not the metabolic complications of hyperglycemia or ketoacidosis, were behind this high mortality rate. Patients who died were significantly (P = 0.004) older than patients who were discharged alive. Conclusion: Results concerning precipitating factor were similar to the results of many other studies. However, mortality rate was higher which might be explained by the severity of underlying precipitating illness.
format	article
author	Zaynab Alourfi Hakam Homsi
author_facet	Zaynab Alourfi Hakam Homsi
author_sort	Zaynab Alourfi
title	Precipitating factors, outcomes, and recurrence of diabetic ketoacidosis at a university hospital in Damascus
title_short	Precipitating factors, outcomes, and recurrence of diabetic ketoacidosis at a university hospital in Damascus
title_full	Precipitating factors, outcomes, and recurrence of diabetic ketoacidosis at a university hospital in Damascus
title_fullStr	Precipitating factors, outcomes, and recurrence of diabetic ketoacidosis at a university hospital in Damascus
title_full_unstemmed	Precipitating factors, outcomes, and recurrence of diabetic ketoacidosis at a university hospital in Damascus
title_sort	precipitating factors, outcomes, and recurrence of diabetic ketoacidosis at a university hospital in damascus
publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate	2015
url	https://doaj.org/article/1609218cbded47ba851c6f98a08219e2
work_keys_str_mv	AT zaynabalourfi precipitatingfactorsoutcomesandrecurrenceofdiabeticketoacidosisatauniversityhospitalindamascus AT hakamhomsi precipitatingfactorsoutcomesandrecurrenceofdiabeticketoacidosisatauniversityhospitalindamascus
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Precipitating factors, outcomes, and recurrence of diabetic ketoacidosis at a university hospital in Damascus

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