Real-time monitoring of PARP1-dependent PARylation by ATR-FTIR spectroscopy

Real-time monitoring of PARP1-dependent PARylation by ATR-FTIR spectroscopy

The mechanism of PARP1-dependent poly-ADP-ribosylation in response to DNA damage is still under debate. Here, the authors use ATR-FTIR spectroscopy to provide time-resolved insights into the molecular details of this process under near physiological conditions.

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Detalles Bibliográficos
Autores principales: Annika Krüger, Alexander Bürkle, Karin Hauser, Aswin Mangerich
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/1616d84778de4c2386df75ff6b8c0ab3
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